Skin, Hair, Nail Flashcards
Block 2 - Dr. M + Dr. W (74 cards)
Common integument
skin with all covering
Role of Skin
covers + protects, temperature control, responds to stimuli, communcation with hair via piloerection.
Layers of Skin
epidermis, dermis, subcutaneous layer, accessory structures
Epidermis
outer most multi layer
Dermis
underlay of tough connective tissues
Subsutaneous
subcutis or hypodermis
Accessory structures of skin
hair, feather, gland
Function of epidermis
stratified squamous, protective layer that provided “water-proofing”, stops micros invading, non vascular
4 layers of epidermis
Stratum : corneum, granulosm, spinosum, basale
Stratum corneum
tightly connected dead cells
Stratum Grandulosm
flatten further, made of keratin
Stratum Spinosum
connected by desmosomes, even flatter
Stratum basale
stem cells, base layer
4 cells types
keratinocytes, melanocytes, langerhan’s, Merkel
Keratin
insoluble, filament protien connecting high cystenine amount, flexiable when hydrated and cracks when dehydrated
Physiological keratinixation
callus
Melanocytes
determines skin coloration, dispersed between all layers, effects hair coloration
Regulation of pigment synthesis
melanocytes stimulating hormone secreted by pituitary, stimulates production of melanocytes
Cholecalciferol
produced by keratinocytes under UV radiation, through liver then kidneys, calcitriol effects calcium metabolism
Langerhan’s cells
dendritic cells, antigen presenting, first line
Merkel’s cell
modified found in hassle, most abundant where seneor perception is acute, provide sense of touch
Skin permeability
keeps certain things out, permeable to lipid-soluble products
Dermis
Dense, fibrous tissue, thick + vascularized (gives strength), cells surrounded by collagen bundles, houses sweat + sebaceous glands, sensory nerve fibers, papillae that form hair + feathers
Cells found in dermis
fibroblasts, macrophages, leukocytes, mast cells