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Flashcards in Spondyloarthritis Deck (10):
1

Earliest radiological appearance of ankylosing spondylitis in spine?

Blurring of the upper and lower vertebral rims at the thoracolumbar junction (best seen on a lateral x-ray)
-this is caused by enthesitis at the insertion of the intervertebral ligaments

2

What is a syndesmophyte?

A syndesmophyte is a bony growth originating inside a ligament, commonly seen in the ligaments of the spine
-in ankylosing sphondylitis, they cause bony ankylosis and permanent stiffening

3

What is bamboo spine?

Calcification of the intervertebral ligaments and fusion of the spinal facet joints and syndesmophytes

4

Most common pattern of psoriatic arthritis?

Distal interphalangeal arthritis
Pencil in cup!!

5

Allele common in spondyloarthritis?

HLA-B27

6

Common age and gender affected in Spondyloarthritis?

Males, late teens-early 30's

7

Non-spinal complications associated with spondyloarthritis?

Uveitis and Costochondritis

8

Treatment of Ankylosing Spondylitis

NSAID (improve sleep, pain control and exercise compliance)
Methotrexate for peripheral arthritis (not effective in spinal disease)
TNF alpha blocker ADALIMUMAB has changed lives

9

Percentage risk of passing HLA-B27 to children if you have ankylosing spondylitits?

50%

10

A syndesmophyte is a bony growth originating in a what?

Originates in the ligament ;)