Structure of Genome Part 1 Flashcards Preview

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Flashcards in Structure of Genome Part 1 Deck (16):
1

C value

- amount of DNA in unreplicated haploid genome
- length in bp or meters
- mass in grams

- can be expressed in different ways

2

value for genes

- kbp

3

value for genomes

- Mbp or Gbp

4

Tera

10^12

5

Giga

10^9

6

Mega

10^6

7

pico

10^-12

8

femto

10^-15

9

C value for humans at 3 pg

how amount of DNA changes throughout cell cycle

- somatic cells are diploid - 6
- G1 - 6
- S - 6-12
- G2 - 12
- M - 12-6

10

c value comparison

- relationship between complexity and size of organisms

11

C-value paradox

- inability to account for the DNA content of the genomes based on complexity

12

2 problems with c-value paradox

- C value is higher than necessary
- Large variations in C value

13

C value higher than necessary

- most eukaryotes have more DNA than needed to code for all the proteins

14

large variations in C-value

- for closely related organisms whose apparent complexity varies little.

15

junk DNA

- DNA in the nucleus that has no known function
- could be involved in organizing or regulating replication of the genome

16

repetitive DNA

- a large fraction of the DNA in eukaryotes consists of a few millon bp that are repeated hundred or even millions of times
- the c value is low in this case