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Flashcards in Structure of Genome Part 4 Deck (5)
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1

the relationship between size and complexity in genomes

- in genomes with repetitive DNA, the sequence of each type of repeat adds to the complexity only once, no matter how often it is repeated.

2

why Cot curves containing various components of repetitive DNA have several phases.

- repetitive DNA reassociates first because it's more concentrated
- then lag phase
- then unique DNA will reassociate

3

which reassociates faster

- repetitive DNA because it is less complex

4

why plot Cot

- experiments using a single concentration of DNA would take years

5

calculating the complexity

Co1/2 (genome or portion of genome) / Cot 1/2 E. coli DNA
= complexity of any genome or portion of genome/ complexity of E. coli DNA (4.2*10^6)