Substance Use Disorder Flashcards

(47 cards)

1
Q

Most important element

A

Build a trusting relationship with the

patient

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2
Q

Assessment for SUD

A
Obtain a thorough medical history
• Know s/s of substance use,
withdrawal symptoms specific to each
substance
• Build a trusting relationship with the
patient
• Non-judgmental, empathetic attitude
• Be aware of resources in the community
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3
Q

ETOH Intoxication S/S

A

Slurred speech, Dizziness,
Incoordination, Unsteady gait,
Nystagmus, Impaired attention/memory,
Coma or double vision

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4
Q

ETOH Withdrawal 8 to 12 hours

A
Autonomic hyperactivity (hight BP, increased heart rate etc);
Perceptual disturbances and hallucinations
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5
Q

ETOH Withdrawal 12-24 hours

A

Generalized/tonic-clonic seizures

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6
Q

ETOH Withdrawal other

A

Nausea, vomiting; can be life-threatening

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7
Q

CIWA Categories

A
Agitation (0–7)
Anxiety (0–7)
Auditory Disturbances (0–7)
Clouding of Sensorium (0–4)
Headache (0–7)
Nausea/Vomiting (0–7)
Paroxysmal Sweats (0–7)
Tactile disturbances (0–7)
Tremor (0–7)
Visual disturbances (0–7)
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8
Q

CIWA <10

A

supportive, n on-pharmacologic therapy and close monitoring are indicated )unless patient has hx of alchol withdrawl seizures or co-morbid cardiovascular conditions

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9
Q

CIWA 10 - 15

A

Lorazepam is indcated to reduce symptoms and the risk of major complications

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10
Q

CIWA >15

A

Strong consideration should be given to hospitalizing inmates who exhibit severe symptoms, as they are at increased risk for serious complications

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11
Q

ETOH WD treatment drugs

A

Benzodiazepines, anticonvulsants
(carbamazepine, gabapentin), clonidine,
propranolol

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12
Q

ETOH treament supplement

A

Thiamine

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13
Q

Why do we use thiamine

A

B1 deficiency can occur with chronic ETOH use. This results in wernkeis encephalopathy. Confusion CNS effects

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14
Q

Naltrexone

A

mu opioid receptor antagonist - used in ETOH disorder

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15
Q

Acamprosate used in ETOH MOA

A

binds to and blocks glutamate

receptors

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16
Q

Disulfiram

A

irreversibly inhibits aldehyde

dehydrogenase preventing metabolism of alcohol

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17
Q

Opioid Intoxication S/S

A
Pinpoint pupils; Psychomotor
retardation, “nodding off;” Drowsiness,
slurred speech; Impaired memory and
attention; Reduced respirations, respiratory
depression or distress
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18
Q

Opioid Withdrawal

A

Dilated pupils, yawning, runny
nose/tearing; Piloerection; Restlessness,
muscle aches; Stomach cramps, diarrhea,
tachycardia; tremors (less common), hot/cold
sweats, insomnia; feels life threatening to the
person

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19
Q

COWS categories.

A
Resting heart rate (0–4)
Gastrointestinal upset in past
30 minutes (0–5)
Sweating (0–4)
Tremor of hands (0–4)
Restlessness (0–5)
Yawning during assessment (0–4)
Pupil size (0–5)
Anxiety or irritability (0–4)
Bone or joint aches associated with
withdrawal (0–4)
Gooseflesh skin (0–5)
Runny nose or tearing (0–4)
20
Q

COWS mild

21
Q

COWS Moderate

22
Q

COWS moderately severe

23
Q

COWS severe

24
Q

Treatment of opoids includes

A

alpha-2 adrenergic

agonists

25
Drugs used to treat OUD
Buprenophine, Methadone, Nextrexone, Naloxone
26
Bupreophine class
mu receptor partial agonist
27
Methadone class
Full opoid agonist
28
Naltrexone class
mu opoid receptor atnagonist
29
Benzo withdrawal symptoms
sx similar to alcohol | withdrawal
30
Benzo withdrawal starts
starts 2-3 days after cessation or up to 5 with long acting; can be life threatening
31
Do not prescribe ____ on a long term basis
benzos
32
Cannabis Intoxication S/S
Red eyes (dilation of conjunctival blood vessels, mild tachycardia, dry mouth; Heightened sensitivity to environmental stimuli, Slowing perception of time; Depersonalization, Derealization; Impaired memory, increased appetite; Delirium, paranoia, or psychosis; Impaired motor skills and attention (up to 8 to 12 hours after use)
33
Cannabis Withdrawal starts
1-2 weeks of cessation
34
Cannabis S/S
Irritability, cravings, headaches; Anxiety/restlessness, tremors; Insomnia, vivid dreams; Decreased appetite, wt loss, stomach pain; Hyperemesis syndrome
35
Nicotinic acetylcholine receptor agonist - half life
2 hour
36
Nicotine activates
dopamine vTa pathway, increases endogenous epinephrine and norepinephrine
37
nicotine has
stimulant effects on the body
38
Nicotine intoxication
skeletal muscle relaxation, improved | attention, learning, reaction time and probelm- solving (short term); decreased appetite
39
Nicotine withdrawal begins
within 2 hours and peaks 24 to 48 hours
40
Nicotine withdral S/S
Insomnia; Increased coughing (short- term); Irritability, cravings, tension; Increased appetite, weight gain; Poor focus
41
Nicotine Replacement therapy
Relieve nicotine withdrawal symptoms by providing nicotine | without the use of tobacco
42
NRT Side Effects
common to all NRT: GI symptoms, HA, local irritation
43
NRT forms
Patch, gum, lozenges, inhalers, nasal spray, mouth spray, SL | tablets
44
Varenicline (Chantix)
partial nicotine agonist
45
Varenicline (Chantix) MOA and use
Reduces the symptoms of nicotine withdrawal • Blocks nicotine from binding to the receptor that mediates the reinforcing effects of nicotine that leads to nicotine dependence. • Reduces rewarding aspects of cigarette smoking.
46
Bupropion (Zyban)
antidepressant,
47
Bupropion (Zyban) MOA and use
dopamine/norepinephrine-reuptake inhibitor | • Enhances CNS noradrenergic and dopaminergic release