Substance Use Disorders Flashcards Preview

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Flashcards in Substance Use Disorders Deck (41)
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1
Q

Psychoactive substance

A

Substance that when ingested alters mood, thoughts, or behavior

2
Q

Substance use

A

Using substances in controlled manner

3
Q

Tolerance

A

Requiring more of substance to get same effect

4
Q

Withdrawal

A

Symptoms that develop after stopping use of a substance after chronic use

5
Q

Substance intoxication

A

A reversible syndrome due to recent ingestion of a psychoactive substance
Physiological, behavioral, and mood changes
Varies across substances
Impairment: most important aspect

6
Q

Substance use disorder

A

Pattern of use lasting 12 months and associated with significant impairment
Symptoms: taking more than intended, persistent desire to quit/unsuccessful attempts to quit, great deal of time spent on substance, craving/strong desire to use, failure to fulfill major roles, persistent social problems, important activities given up, use in hazardous situations, exacerbation of known condition, tolerance, withdrawal when stopped

7
Q

How severity of a substance use disorder is measured

A

of symptoms, not how much is used

8
Q

Depressants mechanism

A

Depress CNS activity

9
Q

Types of depressants

A

Alcohol
Barbiturates
Hypnotics (Ambien)
Benzodiazepines (usually used to treat anxiety; Xanax, Valium, Rufies, etc.)

10
Q

Neurotransmitter depressants act upon

A

GABA: increase

11
Q

Intoxication symptoms of depressants

A

Slurred speech
Incoordination
Nystagmus (involuntary jerkiness of eyes)

12
Q

Withdrawal symptoms of depressants

A

Medically dangerous
Hand tremors
Hallucinations
Seizures

13
Q

Long-term effects of alcohol abuse

A

Liver damage (cirrhosis)
Cognitive impairment: Wernicke-Korsakoff’s (memory impairment, delusions, confusion)
Pancreatitis
Cardiovascular issues

14
Q

Epidemiology of alcohol usage

A

50% of Americans drink
23% of Americans binge drink (4+ drinks for women; 6+ drinks for men)
17% of Americans qualify for alcoholism at some point in their lifetimes (more males than females)
Alcoholism has a progressive course (~20% remit)

15
Q

Stimulants mechanism

A

Stimulate CNS activity

16
Q

Types of stimulants

A

Amphetamines (meth, ecstasy)
Cocaine (different forms: intensity depends on how fast it enters bloodstream)
Nicotine
Caffeine

17
Q

Neurotransmitters acted upon by stimulants

A

Amphetamines and cocaine: increase dopamine

Nicotine: acetylcholine

18
Q

Intoxication symptoms of stimulants

A

Tachycardia (racing heart)
Decreased appetite
Chest pain
Seizures

19
Q

Withdrawal symptoms of stimulants

A

Not medically dangerous
Fatigue
Vivid dreams (usually nightmares)
Depression

20
Q

Effects of meth on body

A

Teeth erosion
Sores from picking at skin
Gaunt from not eating

21
Q

Effects of opioids

A

Analgesic (painkiller)

Euphoria

22
Q

Types of opioids

A

Heroin
OxyContin
Morphine

23
Q

Neurotransmitter acted upon by opioids

A

Endorphins (pain relieving effects and euphoric effects)

24
Q

Intoxication symptoms of opioids

A

Pupil dilation/contraction
Drowsiness (or coma)
Slurred speech

25
Q

Withdrawal symptoms of opioids

A

Not medically dangerous
Excessive yawning
Nausea
Piloerection (goosebumps)

26
Q

Effect of hallucinogens (psychodelics)

A

Alter perceptions (not necessarily hallucinations)

27
Q

Types of hallucinogens

A

Marijuana
LSD
Psilocybin (peyote)
Mescalin (shrooms)

28
Q

Neurotransmitter acted upon by LSD

A

Serotonin

29
Q

Intoxication symptoms of marijuana

A
Conjunctival injection (red eyes)
Increased appetite (munchies)
Dried mouth
Tachycardia (racing heart)
Psychomotor retardation
30
Q

Anomaly of marijuana

A

Minimal or reverse tolerance (more you use, the less it takes to get high)

31
Q

Withdrawal from hallucinogens

A

Withdrawal is minimal

32
Q

Intoxication symptoms of LSD

A

Perceptual changes
Sweating
Blurred vision
Incoordination

33
Q

Inhalents

A

Volatile solvents breathed directly into lungs (spray paint, hair spray, paint thinner, gasoline, nitrous oxide)
Effects similar to alcohol
Tolerance/withdrawal common

34
Q

Anabolic steroids

A

Derived from testosterone
Medical uses and increased body mass
Doesn’t produce a physiological high
Can result in long-term mood disturbances and physical problems

35
Q

Dissociative anesthetics

A

Cause drowsiness, relieve pain, cause dissociations (become separate from who you are)
Examples: PCP (angel dust), ketamine (special K), bath salts

36
Q

Designer drugs

A

Synthetic drugs produced to mimic the effects of illegal drugs
Don’t contain illegal substances (change compound slightly)
An effort to stay ahead of the law

37
Q

Genetic influence of substance abuse disorders

A

Strong genetic component
Reward sensitivity (likelihood to get positive effects from substance use)
Differences in metabolism

38
Q

Cognitive influences of substance abuse disorders

A

Expectancy effects (affects you how you think it’s going to affect you)
Cravings (drug cues cause desire to use)
Using is not usually an active choice

39
Q

Agonist substitution

A

Treatment of substance abuse disorders
Give medication that acts on same neurotransmitter as substance
Safer, controlled

40
Q

Antagonist substitution

A

Treatment of substance abuse disorders

Give medication that blocks positive effects of substance

41
Q

Aversive treatment

A

Treatment of substance abuse disorders
Make use extremely unpleasant
Give medication along with substance to make person sick