Temperature homeostasis Flashcards

1
Q

What does it mean that humans are homeothermic?

A

They are warm-blooded.

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2
Q

Why does the body temperature need to be maintained within narrow limits?

A

It is essential for the maintenance of normal bodily processes.

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3
Q

What is the normal human average body temperature?

A

36.7+/- 0.5 degrees celsius.

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4
Q

What can alter the measured human body temperature?

A

Sampling site, age, gender and time of day e.g. oral, rectal or tympanic.

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5
Q

Why does the body temperature increase during the second half of the menstrual cycle?

A

The effects of progesterone.

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6
Q

What are sources of heat input?

A

Internal production and external input such as metabolism and muscle contraction and from the environment via radiation or conduction.

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7
Q

What are some sources of heat losses to the environment?

A

Radiation, conduction, convection and evaporation.

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8
Q

What accounts for heat losses in the body?

A

20-30% is from sweating and respiration and 70% is from radiation.

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9
Q

What is the thermoneutral zone?

A

The range of ambient temperature over which the heat from the basal metabolism is sufficient to maintain the body core.

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10
Q

What is the ambient temperature?

A

The environmental temperature.

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11
Q

What is the main physiological thermoregulatory challenge?

A

Low temperature.

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12
Q

What temperature can naked humans thermoregulate at?

A

Between 10-55 degrees celsius.

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13
Q

Where is the thermoregulatory centre?

A

In the hypothalamus.

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14
Q

What does the hypothalamus do?

A

It integrates sensory input from thermoreceptors located in the core and periphery (skin).

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15
Q

Where is an increase blood temperature detected?

A

The anterior hypothalamus.

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16
Q

Where is a decrease in blood temperature detected?

A

The posterior hypothalamus.

17
Q

What might happen if the temperature is above 37 degrees?

A

Sweating, cutaneous vasodilation.

18
Q

What might happen if the temperature is below 37 degrees?

A

Cutaneous vasoconstriction and horripilation, non-shivering thermogenesis in infants and shivering in adults.

19
Q

What detects a change in environmental temperature?

A

Peripheral thermoreceptors.

20
Q

What detects a change in core body temperature?

A

Central thermoreceptors.

21
Q

How does vasodilation cause heat loss?

A

Blood flows closer to the skin so heat can be lost.

22
Q

How does vasoconstriction cause heat gain?

A

There is decreased blood flow towards the surface of the skin so there is decreased heat loss.

23
Q

What does the effectiveness of sweating as a way to lose heat dependent on?

A

Low environmental humidity and free access to water and sodium.

24
Q

What is shivering?

A

Voluntary and involuntary muscular thermogenesis.

25
Q

What is non-shivering thermogenesis?

A

A hormone induced uncoupling of mitochondrial oxidation from phosphorylation in brown adipose tissue. It is only significant in infants.

26
Q

What is hypothermia?

A

A reduced body temperature outside of the normal range.

27
Q

What is hyperthermia?

A

An increased body temperature above the normal range.

28
Q

What is a fever?

A

The result of a chemical resetting of the thermal set point - temperature above 38 degrees. The body temperature stabilises at a new elevated set point.

29
Q

What is the effect of endogenous pyrogens being released into the body?

A

They cause an increase in the thermoregulatory set point in the hypothalamus.