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Flashcards in The LIst Exam 4 Deck (29):
1

Adenovirus

Linear, double stranded DNA
Non-enveloped
Usually respiratory infection… colds (can cause rash, conjunctivitis, gastroenteris)
Birds, humans, mammals

2

Human papillomavirus
(HPV)

DNA
Infects skin and mucous membranes
30% of people have it… most common viral STD

3

Smallpox Virus

Variola virus
Double stranded DNA
Enveloped and uneveloped Skin rash and blisters of skin, mouth, throat.
Eradicated through vaccines
Airborne transmission (droplets)

4

Vaccinia virus (cowpox)

Enveloped
Linear double stranded DNA
Cowpox
Used to eliminate smallpox

5

Herpes simplex virus
(HSV1/2 or HHV1/2)

Double stranded linear DNA
Enveloped
Oral herpes: sores in mouth
90% of people in US have contact by age 50
can be dormant… lessions last 2-3 weeks
no cure

6

Cytomegalovirus (CMV)

DNA viruses

Can cause lytic (latent) infections
Genus of Herpesvirus

Species that infects humans is human CMV

7

Hepatitis B virus

Partially double stranded DNA and circular

Very small genome
Spread through blood and sexual contact

Abdominal pain, dark urine, yellowing of skin, nausea, loss of appetite, joint pain

8

Rhinovirus

Single stranded positive RNA
Non-enveloped
Aerosolized or direct contact
Cold infections
Late summer and late spring

9

Norovirus

ssRNA, (-) strand
non-enveloped
Person to person, foodborne, waterborne
Extremely infectious
Vomiting and diarrhea, nausea, cramps, chills, headache, fever half the time

10

Measles Virus

ssRNA (-)
enveloped
Morbillivirus
Just humans, no animals
Respiratory system: fever, coughm runny nose, rash
Very contagious: coughing and sneezing

11

Mumps Virus

Rubulavirus
ssRNA (-)
enveloped
Childhood disease: swelling of parotid and salivary glands
High morbidity
Deafness
Vaccine-preventable

12

Dengue Fever

ssRNA (+)
enveloped
Mosquito borne
4 serotypes, all cause disease
fever, headache, muscle and joint pain, skin rash like measles

13

West Nile Virus

ssRNA (+)
enveloped
same family as dengue and yellow fever
Mosquito borne
Fever, headache, rash, swollen lymph glands, stiff neck, paralysis

14

Yellow Fever Virus

ssRNA (+)
Decreased number of neutrophils
Blood in urine and feces
Liver dysfunction
Jaundice
Starts like minor flu

15

Ebola Virus

ssRNA (-)
enveloped
Hemorrhagic fever
High fatality

16

Hantavirus

ssRNA (-) enveloped
Haemorhagic feverl with renal syndrome
Rodents
Aerosolization and rodent bites
Pneumonitis, congestion,

17

Rabies Virus

ssRNA (-)
Enveloped
Salvia of animals
Travesl acros PNS quickly to CNS\
Spread to organs… projectile salivation
Death after 2 years to 5 days

18

Influenza Virus

Usually ssRNA (-), sometimes double
Spread through air from cough/sneeze

19

Merkel cell polyomavirus

dsDNA
non-enveloped
Human tumor viruses: cause 80% of Merkel cell carcinoma
Limitied sun exposure can prevent virus

20

Human immunodeficiency
virus (HIV)

ssRNA (+)
Causes AIDS

21

Rotavirus

dsRNA
sometimes enveloped
Resistant to hand washing
Children
Diarrhea
Lots of yearly deaths

22

Hepatitis C virus

ssRNA (+)
enveloped
Can occur with Hep B
Many also have a chronic infection
Attacks liver
Usually asymptomatic… can have fever, poor appetite, tired feeling

23

Epstein Barr virus (EBV or
HHV4)

dsDNA
enveloped
Only humans
Infectious mononucleosis: fever, sore throat, tonsillitis,
Cause disease by lysis of host cell or latency cycle

24

Kaposi’s sarcomaassociated
herpesvirus
(KSHV or HHV8)

dsDNA
Herpesvirus family
Causes cancer (Kaposis sarcoma), esp in AIDS patients
Castlesman’s disease
Cancer virus
Primary effusion lymphoma
Infection though to be lifelong, but can be kept in check if healthy person
Most don't show symptoms unless immunocompromised

25

Varicella zoster virus (VZV
or HHV3)

dsDNA
enveloped

Chicken pox!
Also shingles

26

Severe acute respiratory
syndrome (SARS) virus

ssRNA (+)
enveloped
Muscle pain, headache, fever then
Coughm dyspnea, pneumonia
Decreased lymphocytes in blood
9% die

27

Chikungunya virus

ssRNA (+)
enveloped
Sudden fever for a week to 10 days
Joint pain and stiffness (weeks to years)
Rash, muscle pain, inflammation of eyes
Can be chronic

28

Middle East Respiratory
Syndrome (MERS) virus

ssRNA (+)
From bats, camels: can be transmitted human to human?
Fever, cough, shortness of breath

29

Enterovirus D68

ssRNA (+)
non-enveloped
POLIO: fever, sore throat, headache, vomiting, stiffness of back/neck/limbs
No animals, just human
Enters through mouth, multiplies in intestine
Summer time in temperate
Children under age 5