The role of endogenous hormones in muscle hypertrophy

Question 1

What is testosterone important for?

Answer 1

adaptations to resistance training
-the major promotor of muscle growth and muscle strength in resistance training in men

Question 2

What does the acute endocrine response to heavy resistance training include?

Answer 2

• secretion of various catabolic (breakdown) and anabolic (growth) hormones including testosterone

Question 3

What is sensitive to homogenous hormone volume?

Answer 3

load-intensity
training volume
rest interval
exercise muscle mass and order
(altering these variables will influence hypertrophy)

Question 4

What training is critical for elevating circulating hormones (which is assumed t influence hypertrophy)?

Answer 4

resistance training

Question 5

What does no exercise and steroid produce?
what does this mean?

Answer 5

increase free fat mass and increase strength
-greater response when exercise is included
Meaning- endogenous hormone response must play an important role in muscle hypertrophy

Question 6

Phosphorylation of ____ is an indicator of mTORC1 activity?

Answer 6

S6K1

Question 7

What effect does exercise have on testosterone?

Answer 7

over 7 days there is a sustained increased in testosterone (Schraeder and West, 2013)

Question 8

What happens when you perform larger muscle group exercises first in an upper body resistance training session?

Answer 8

significantly greater growth hormone response
-Trained biceps alone = low hormone response
-trained biceps after training the lower limbs = high hormone response (West et al, 2010)
(long term there was no difference between groups in muscle mass and strength)

Question 9

How many folds lower is women’s testosterone concentration in comparison to men?

Answer 9

~10-15 fold

Question 10

What tendons are collagen levels higher in?

Answer 10

tendons treated with exercise serum meaning the tensile load was higher (West et al, 2015)