Theraputic Proteins Flashcards Preview

IHO > Theraputic Proteins > Flashcards

Flashcards in Theraputic Proteins Deck (21):
1

Darbopoietin

Erythroid Growth factor Short half life. Used for chronic kidney disease, anemia. Side effects are thrombus, hypertension and increased tumor growth.

2

Erythropoietin

Erythroid Growth factor. Used for chronic kidney disease, anemia. Side effects are thrombus, hypertension and increased tumor growth.

3

M-Peg-epoetin

Erythroid Growth factor. Used for chronic kidney disease, anemia. Side effects are thrombus, hypertension and increased tumor growth.

4

Filgrastim

(G-CSF) Myeloid Growth factor. Used to make neutrophils, commonly used for cancer chemotherapy. Can have allergic reaction and splenic rupture, mild bone pain.

5

Pegfilgrastim

Myeloid Growth factor. Longer half life than Filgrastim, Used to make neutrophils, commonly used for cancer chemotherapy. Can have allergic reaction and splenic rupture, mild bone pain.

6

Sargramostim

(GM-CSF) Myeloid Growth factor. Stimulates all myeloid cell production. Can have capillary leak syndrome(edema), bone pain, fever, malaise, and occasionally allergic reaction.

7

Interleukin 11

Megakaryocyte Growth factor. Used to increase platelet production. Causes autoantibodies to be produced. Can cause A-Fib, and hypokalemia. May cause fatigue, headache, dizzyness, mild edema.

8

Romiplostim

Megakaryocyte Growth factor. Used to increase platelet production. Causes autoantibodies to be produced. Can cause A-Fib, and hypokalemia. May cause fatigue, headache, dizzyness, mild edema.

9

Most to least human

U, ZU, Xi, Mo(O) (Human, Humanized, Chimeric, Mouse) mouse also most likely to cause allergic/ other response.

10

Cir

Cardiovascular

11

vir

viral

12

lim

Immune

13

Les

infectious lesions

14

col

colon

15

mel

melanoma

16

mar

mamary

17

got

testes

18

gov

ovary

19

pr (o)

prostate

20

tum

misc tumor

21

HAMA reaction

Human antimouse reaction