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Flashcards in thyroid Deck (23)
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1

hypothyroid treatment

levothyroxine

2

1 pituitary hypothyroid cause

hypopituitarism form non functioning adenoma

3

thyroid causes of hypothyroid

Thyroidectomy
post radioactive iodine ablation 

Autoimmune
thyroiditis- postpartum, silent, Hashimoto’s
blocking TSH receptor antibodies

4

2 congenital causes of hypothyroid

Thyroid dysgenesis (85%)
Dyshormonogenesis

5

4 causes of Dyshormonogenesis

Thyroid peroxidase
  thyroglobulin
  sodium iodide symporter
  pendrin   (Pendred syndrome) - deafness and hypothyroidism

6

Maternal thyroid disease
Neonatal hypothyroidism/cretinism
symtoms

•Coarse facial features
•Macroglossia
•Large fontanelles
•Umbilical hernia
•Mottled, cool, and dry skin
•Developmental delay
•Pallor
•Myxedema
•Goiter

7

Hyperthyroidism
Investigation

TSH - free T4 and total T3
TSH receptor antibodies
TPO- thyroid peroxisomal antibody
123 I uptake scan

8

Hyperthyroidism symtoms

Eye symptoms
Petibial myxedma
Thyroid acnopalsty

9

Treatment of hyperthyroid

Beta blockers
Carbimazole  40 mg daily (propylthiouracil)
OR
131I  (radioactive iodine)

10

pituitary cause of hyperthyroid

Pituitary adenoma

11

other hormone acting as TSH causing hypothyroid

HCG

12

Thyroid causes of hyperthyroid

Autoimmune
thyroid adenoma 

13

what gives a thyroid bruit

graves

14

how does amidoarone work

Amiodarone - releases iodine , good for AF

15

Jod Basedow phenomenon:

iodine induced  hyper  thyroidism

16

Wolff Chaikoff effect

iodine induced  hypo    thyroidism

17

Amiodarone thyroid disease
type 1
and treatment

autoimmune thyrotoxicosis - unmasking a previous thyroid disease
  treatment high dose carbimazole

18

Amiodarone thyroid disease
type 2
and treatment

destructive thyroiditis
  treatment glucocorticoids / steroids

19

Proptosis increases risk of

corneal ulceration

20

what kind of cancer if thyroid c cell

medullary cancer

21

4 thyroid carcinomas

Papillary
Follicular
Anaplastic
Poorly Differentiated

22

Meduallary thyroid cancer

Cancer of parafollicular (calcitonin)  producing thyroid  cells
Familial

23

3 diseases associated with Mutations of RET protoncogene

Familial Medullary Thyroid Cancer
Multiple Endocrine Neoplasia type 2 and 3  (MTC, phaeochromocytoma, primary hyperparathyroidism)
Hirschprungs