Thyroid and Parathyroid Flashcards

1
Q

What is a goiter?

A

enlargement on the thyroid from excess TSH, decreased iodine,

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2
Q

What is hypothyroidism?

A

a disease in which insufficient amounts of T3 and T4 are produced

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3
Q

What is the most common cause of hypothyroidism?

A

Hashimotos disease

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4
Q

Who is most at risk for hypothyroidism?

A

females over 50 who are white, have been pregnant before, have a genetic link, history of autoimmune disorders, or are being treated for hyperthyroidism

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5
Q

What are early signs of hypothyroidism?

A

cold intolerance, weight gain, fatigue, lethargy, memory deficits, muscle cramps, increased carotene and cholesterol, puffy face, hair loss, brittle nails

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6
Q

What are the late signs of Hypothyroidism?

A

decreased temperature, bradycardia, thick skin, yellow skin, HLD, weight gain, cardiomegaly, myxedema

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7
Q

What will your labs look like in Hypothyroidism?

A

increased TSH, decreased T3 and T4, anti-thyroid antibodies, anti-TPO

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8
Q

What is the hallmark sign of hypothyroidism?

A

anti-TPO (thyroperoxidase)

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9
Q

What is hyperthyroidism?

A

excessive T3 and T4 secretion

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10
Q

what is primary hyperthyroidism stemming from?

A

thyroid

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11
Q

What is secondary hyperthyroidism stemming from?

A

pituitary

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12
Q

What is tertiary hyperthyroidism stemming from?

A

hypothalamus

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13
Q

what risk factors are associated with hyperthyroidism?

A

family history, over 40, women, caucasian, pregnant, excess idoine intake

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14
Q

what is graves disease?

A

excess T3 and T4, thyroid stimulating antibodies

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15
Q

What are some clinical manifestations of graves disease?

A

nervousness, insomnia, heat sensitivity, weight loss, palpable gland, bruit, A. Fib, EXOPTHALMOAS

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16
Q

What is Exophthalmos?

A

wide-eyed stare and preorbital edema

17
Q

What can you treat Graves disease with?

A

radioactive iodine and propylthiouracil

18
Q

What is a thyrotoxic crisis/thyroid storm?

A

overwhelming release of thyroid hormone that exerts an intense stimulus on the metabolism and is caused by surgery, trauma, or infection

19
Q

What is hypoparathyroidism?

A

decreased parathyroid hormone that causes hypocalcemia

20
Q

What is hyperparathyroidism?

A

increased parathyroid hormone that causes hypercalcemia

21
Q

What are hypocalcemia CM?

A

muscle cramps, irritability, tetany, convulsions, trousseaus (carpal spasam), Chvosteks (facial muscle twitch)

22
Q

What are hypercalcemia CM?

A

muscle weakness, poor concentration, neuropathies, hypertension, kidney stones, metabolic acidosis, osteopenia, pathological fractures, constipation, depression, confusion, cognitive deficits

23
Q

What are hypoparathyroidism treatments?

A

replace parathyroid hormone, calcium, and vitamin D

24
Q

What are some signs and symptoms of a thyrotoxic crisis/thyroid storm?

A

Fever > 103, Tachycardia > 140, A fib, A flutter, N/V, tremor, Psychosis, stupor/coma, Hypotension