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Flashcards in Thyroid Emergencies Deck (15)
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1

What is Myxedema?

Another term for severely advanced hypothyroidism

2

Myxedema occurs secondary to what?

Secondary to infiltration of subcutaneous tissues by a hydrophilic mucopolysaccharide substance

3

What are the clinical features of Myxedema?

Swelling of:
- Face
- Hands
- Lower legs
- Feet

4

What are the diagnostic studies of Myxedema?

↑TSH
↓TH (T4)

5

What is the tx for Myxedema?

Levothyroxine

6

What are the clincial features of myxedema coma?

- Bradycardia
- Hypotension
- Reduced levels of consciousness
- Seizures
- Hypothermia
- Macroglossia, ptosis
- Hx. poor compliance or undiagnosed hypothyroidism

7

What is the mortality rate of myxedema coma?

Highest mortality rate, despite invasive tx

8

Myxedema coma almost always occurs in who and precipitated by what?

- Elderly population
- Impaired respiration

9

What are some examples that can impair your respiration?

- Medications: CNS Depressants: Sedatives, Anesthesia, Antidepressants
- Pneumonia
- Hypoventilation
- CHF
- MI
- GI Bleed
- CVA
- Sepsis
- Cold Exposure

10

What is the tx for myxedema coma?

Levothyroxine 500 ug IV Bolous
External warming if <30 C

11

What is Thyrotoxic Crisis or Thyroid Strom?

Rare life-threatening exacerbation of hyperthyroidism

12

What is the mortality rate of Thyrotoxic Crisis or Thyroid Strom if left untreated?

~ 30% d/t:
- Cardiac Failure
- Arrhythmia
- Hyperthermia

13

Thyrotoxic Crisis or Thyroid Strom is usually precipitated by what acute illnesses?

- CVA
- Trauma
- DKA
- Infection
- Surgery
- Radioiodine Treatment

14

What are the clinical features of Thyrotoxic Crisis or Thyroid Strom?

- Fever
- Vomiting
- Delirium
- Diarrhea
- Seizures/Coma
- Jaundice

15

What is the tx for Thyrotoxic Crisis or Thyroid Strom?

Medical Emergency get to the ER right away!!