Toxicities and Side Effects

Question 1

Treatment for toxicity: Acetaminophen

Answer 1

N-acetylcysteine (replenishes glutathione)

Question 2

Treatment for toxicity: AChE inhibitors, organophosphates

Answer 2

Atropine > pralidoxime

Question 3

Treatment for toxicity: Antimuscarinic, anticholinergic agents

Answer 3

Physostigmine

Control hyperthermia

Question 4

Treatment for toxicity: Arsenic

Answer 4

Dimercaprol

Succimer

Question 5

Treatment for toxicity: BDZs

Answer 5

Flumazenil

Question 6

Treatment for toxicity: Beta-blockers

Answer 6

Atropine
Glucagon
Saline

Question 7

Treatment for toxicity: Carbon monoxide

Answer 7

100% O2

Hyperbaric O2

Question 8

Treatment for toxicity: Copper

Answer 8

Penicillamine

Trientine

Question 9

Treatment for toxicity: Cyanide

Answer 9

Nitrite + Thiosulfate

Hydroxocobalamin

Question 10

Treatment for toxicity: Digoxin (Digitalis)

Answer 10

Anti-digitalis Fab fragments

Question 11

Treatment for toxicity: Heparin

Answer 11

Protamine sulfate

Question 12

Treatment for toxicity: Iron

Answer 12

Deferoxamine
Deferasirox
Deferiprone

Question 13

Treatment for toxicity: Lead

Answer 13

EDTA
Dimercaprol
Succimer
Penicillamine

Question 14

Treatment for toxicity: Mercury

Answer 14

Dimercaprol

Succimer

Question 15

Treatment for toxicity: Methanol

Answer 15

Fomepizole > ethanol

Dialysis

Question 16

Treatment for toxicity: Ethylene glycol (antifreeze

Answer 16

Fomepizole > ethanol

Dialysis

Question 17

Treatment for toxicity: Methemoglobin

Answer 17

Methylene blue

Vitamin C

Question 18

Treatment for toxicity: Opioids

Answer 18

Naloxone

Question 19

Treatment for toxicity: Salicylates

Answer 19

NaHCO3 (alkalinize urine)

Dialysis

Question 20

Treatment for toxicity: TCAs

Answer 20

NaHCO3

Question 21

Treatment for toxicity: Warfarin

Answer 21

Fresh frozen plasma (immediate)
Vitamin K (delayed)