Transfusion Medicine Flashcards Preview

Heme/Lymph > Transfusion Medicine > Flashcards

Flashcards in Transfusion Medicine Deck (20):
1

What infectious diseases are tested for with blood donation?

Hep B, Hep c, HIV, HTLV, Syphilis, West Nile, Trypanosoma cruzi

2

What does the indirect antiglobulin test detect?

Antibodies in the patient's serum

3

Function of cell preservatives -- citrate

Anticoagulant, binds Ca2+

4

Function of cell preservatives--phosphate

Maintains 2,3 DPG levels

5

Function of cell preservatives--dextrose

For cell metabolism

6

Function of cell preservatives--adenine

For ADP/ATP production

7

How much does 1 unit of pRBC's raise the hemoglobin?

1 g/dL in an average sized adult

8

When is transfusion for anemia supported?

<6 g/dL -- but must take into consideration the patients entire presentation

9

When giving pRBC's which ABO type is the universal donor? universal acceptor?

Universal donor--O
Universal acceptor--AB

10

What does 1 unit of Fresh Frozen Plasma do for a patient?

10-15 mL raises all clotting factors by 20-30% in average sized adult

11

When giving FFP which ABO type is the universal donor? universal acceptor?

Universal Donor--AB (no antibodies)
Universal Acceptor--O (Both antibodies)

12

How much does 1 unit of platelets raise the platelet count?

30,000-60,000 for the average sized adult

13

What is the first thing to use for DIC?

Cryoprecipitate -- it contains fibrinogen (and factors VIII, XIII, vWF)

14

What is Febrile Non-hemolytic transfusion reaction (FNHTR)? How do you differentiate between that and Hemolytic transfusion reaction?

Antibodies in recipient against donor WBC's

Patients may have similar symptoms (Chills/backpain/fever_ but hemolytic reaction will show +DAT, hemoglobinuria, increased bilirubin, decreased haptoglobin and increase LDH

15

What can be given for rigors?

Demerol (IV)

16

What is especially important in a case of hemolytic transfusion reaction?

Promote adequate renal blood flow (keep urine output >100 mL/hour with IVF and IV diuretics)

17

What is the #1 cause of death with transfusion?

TRALI = Transfusion related acute lung injury

Patients are SOB, have pulmonary edema, hypotension, fever, tachycardia

18

What are the three reactions to transfusion that may cause SOB?

TRALI
Allergic reaction
TACO = Transfusion associated circulatory overload

19

Is a person hypertensive or hypotensive with TACO?

Hypertensive
Will also have an enlarged heart on CXR?

20

What is the treatment for TACO?

Lasix