Unit 10 - Chapter 7 Flashcards

(75 cards)

1
Q

all medications are poisonous if

A

given to wrong pt or in wrong quantities

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2
Q

what gives you the specifics about a drug

A

drug profile

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3
Q

pharmacology
drugs
dose

A
  • study of the effects of drugs and medication on the body
  • chemical agents used to diagnosis, treat or prevent disease
  • amount of medication given
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4
Q
define
action
intended effect
unintended effects
untoward effects
toxicity
A
  • is the therapeutic effect
  • effect that is expected on the body
  • effects that are undesirable but pose little risk to pt
  • effects that are harmful to pt
  • risk that substance will pose a health hazard to individual
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5
Q

what are the 7 R’s

and 3 C’s and E

A

right person, drug, dose, time, route, documentation, right to refuse

concentration, clarity and color, expiration

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6
Q

drugs are derived from 4 things

A

animal, vegetable , mineral and synthetic

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7
Q

define trade name vs generic vs chemical vs official

A

trade- brand name from manufacturer
generic- usually its original chemical name
chemical- precise description in chemical composition
official- name given by USP

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8
Q

what is the controlled substance act

how are they classified

A

comprehensive legislation dealing with drugs that have a potential for abuse

1-5 , 1 being the highest

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9
Q

sources of drug information

A
cpc
physicians desk reference
hospital forumary
drug inserts
drug evaluations
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10
Q

for a drug to carry a USP label , how much active ingredient must their be

A

95-105 %

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11
Q

average time for a drug to be tested and approved

A

9 years

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12
Q

what is a teratrogenic drug

A

drug that poses a risk to normal development of unborn fetus

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13
Q

how canada rates risk of drugs on pregnancy

A

A-no documented risk
B, no effect animals, not enough tests on humans
C effect on animals, not tested on humans
D- danger to fetus is noted, but may be outweigh risk
X- Adverse effects clear

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14
Q

it is best to withhold pharmacologic treatment when pregnant unless life threatening, when in doubt:

A

contact medical control

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15
Q

young infants have a sharply:

A

reduced metabolic rate

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16
Q

medication is pediatric pts is usually based on

A

body surface area and weight

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17
Q

children many require what with drugs ( 2 )

A

more frequent administration

relatively higher doses

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18
Q

taking several medications can

A

have an effect on mental status

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19
Q

scope of practice with medication states

A

you are morally, ethically and legally responsible to know each drug you administer

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20
Q

how are drugs classified

A

by the effect they have on the body

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21
Q

drugs can be classified by ( 3 )

A
body system
class of agent
mechanism of action
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22
Q

sympathetic nervous system is AKA

A

adrenergic

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23
Q

what are the alpha and beta response

A

alpha 1- peripheral vasoconstriction
alpha 2- peripheral vasodilation ( little or no bronchoconstriction)
beta 1- increased HR
beta 2- bronchodilation and vasodilation

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24
Q

what are sympathomimetics

A

drugs that mimic effect of sympathetic nervous system

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25
what medications inhibit the sympathetic nervous system and other name
sympatholytics ( antiadrenergics )
26
drugs that bind to a receptor and cause a response are called
agonists
27
drugs that counteract the action of something else are called
antagonists
28
what do beta blockers do | used to control
block beta responses | blood pressure and heart rhythm disturbances in others
29
agonists to the parasympathetic system are called
parasympathomimetics
30
antagonist to the parasympathetic system are called also called block what two receptors
parasympatholytics anti-cholinergics muscarinic and nicotinic
31
with excessive cholinergics , pt mass experiences
SLUDGE
32
what is a powerful parasympatholytic
atropine | Eg- excessive bradycardia or exposure to organophosphates
33
what normally binds to cholinergic receptors
acetylcholine ( ACh)
34
most common type of analgesis in pre-hopital
opoid agoinst , CNS depressant
35
what are some non-opioid analgesics
salicylates ( aspirin ) NSAIDS - inprofen para-aminophenol deriatives ( tylonel )
36
what do opioid antagoinists do
reverse effects of opioid drug
37
why are opiod agonist- antagoinists preffered
reduce pain but dont deminish function of respiratory system or lead to addiciton
38
drugs that help pts through surgery , medical procedure | some examples
antianxiety , sedative, hypnotic benzodiazepines , barbiturates
39
what is a seizure in general terms | examples of anticonvulsants
state of neurological hypersensitivity | benzo, barb, hydantoins, valporic
40
stimulants do what and examples | depressants do what and examples
stimulate CNS - caffeine , cocaine | slow CNS- Xanax, ambien
41
what do psychotherapy drugs do | treat illnesses like
block dopamine receptors in brains | schizo, depression
42
medications targeting the cardiovascular system are classified according to their
effects on specialized cells
43
various effects of the drugs are classified in 3 ways
chronotropic - heart rate inotropic- force of contraction dromotropic- velocity of conduction in heart
44
what are cardiac glycosides
derived from plant, block certain pumps in heart cells
45
antiarrhythmic drugs treat and prevent cardiac rhythm disorders, what classifications do they have
sodium- slow conduction potassium- heart contraction calcium - decrease force of contraction
46
ACE inhibitors do what
partially controls BP
47
fibrinolytic agent does what
breaks down blood clot
48
second line of treatment in respiratory emergencies
xanthines - relax smooth muscles of broncioles and stimulate cardiac muscle to work harder
49
corticosterioids do what
suppress inflammation
50
immunosuppressants medication may be used for what and do what
pts undergo transplant or auto immune disease | inhibit bodys ability to attack itself
51
vitamins and minerals are essential for (3)
metabolism, growth and development and cellular function
52
what type of fluid is common is pre-hospital environment and can be 3 categories
crystalloid- dissolved | isotonic, hypotonic and hypertonic
53
define isotonic hypertonic hypotonic
iso- stable medium- fluid / electrolytes hyper- help provide nutrition hypo- dehydration ( not hyopvolemic )
54
manufacturers chose form of drug to ensure 3 things
proper route, time of release and effect on body system or organ
55
route of administration effects
onset of action
56
what is pharmacokinetics
study of metabolism and action of drug
57
4 steps of pharmacokinetics
absorption, distributions , bio transformation and excretion
58
pharmacodynamics | AKA
way in which a medication produces response intended | mechanism of action
59
what property determines the drugs concentration at its site of action
pharmaceutical properties
60
what is drug action
result of physiochemical change between drug and the molecule
61
what effects drug absortion
pH, dosage form, drug concentration, route,
62
what is important during mechanism of action
drug must reach appropriate site at correct concentration
63
what is bioavailabilty
rate and extent drug enters the circulatory system
64
what is therapeutic threshold
minimal concentration to reach desired effect
65
therapeutic index
medications margin of safety LD50 to ED 50
66
factors that effect drug response
age, body mass, sex, environmental conditons, time of administration, genetics, psychological factors
67
define onset of action and duration of action
onset- how long to meet the target | duration- how long drug will stay above minumum level for intended action
68
an interaction between drugs occurs when
actions of drug in body is modified in some way
69
what is a predictable response
anticipated response past desired effect
70
what is a iatrogenic response
adverse condition inadvertently induced in a pt by the treatment given symptoms that mimic naturally occurring diseases
71
what is a unpredictable response and most common
adverse effects that were not anticipated | allergic reaction
72
other unpredictable responses include (7)
``` serum sickness- delayed reaction idiosyncratic- rare , unique response tolerance cumulative effect drug dependence drug interaction summation- addiction ```
73
what effects potency of drugs
temperature , light, moisture , shelf life, exposure to air
74
The enhancement or action of one drug by another drug is called:
potentiation.
75
What is an enteral drug?
administered anywhere along GI tract