Unit 13 - Lymphatic System Flashcards
Lymphatic system consists of
- one way network of lymphatic vessels that collect approximately. 10% of the ECF that leaked out from cardiovascular capillaries and return this fluid to the venous blood
- lymph nodes along the vessel network that cleanse lymph as it passes through them
What support the functions of the lymphatic system
- lymphoid cells
- tissues
- organs
ICF
- intracellular fluid
- fluid found within cells
ECF
- fluid found outside of cells
Blood plasma
- ECF
- fluid in blood
- some exits capillaries to for ISF (interstitial fluid)
ISF
- interstitial fluid
- fluid between cells within the body (except blood cells which are surrounded by plasma)
- some moves into lymphatic capillaries to form lymph
Lymph
- approx. 1% of body weight
- fluid inside lymphatic system
- returned to blood plasma
Lymphatic circulation
Write out on whiteboard page 78 of notes
Lymphatic capillaries
Closed ended vessels that project into cardiovascular capillary beds
- lymphatic capillaries in the small intestine also play a role in fat absorption
What filters lymph
Lymph nodes along collecting vessels filter lymph (bacteria debris)
Where do lymphatic capillaries transport lymph fluid away from tissue to
- Right lymphatic duct
- Thoracic duct
Right lymphatic duct
- lymph from the right side of the head, chest and arm
- drains into right subclavian vein re-entering circulation
Thoracic duct
- lymph from below the ribs and the entire left side of body
- collecting vessels form below the ribs converge to an enlarged lymph vessel (cisterna chyli- most inferior portion of the duct)
- the thoracic duct drains into the left subcalvian vein reentering blood circulation
Summary of lymphatic circulation
One way route back to blood
Lymphatic capillaries - lymphatic collecting vessels (with valves) - lymphatic ducts - subclavian veins
Lymphoid tissues and organs contain
Many lymphocytes and play a key role in the body’s immune system
Primary lymphoid organs and tissues are the locations for what?
- where lymphoid stem cells divide and mature (become immunocompetent)
- includes:
1. Red bone marrow
2. Thymus gland
Where do mature lymphocytes go
Move into bloodstream and migrate to the secondary lymphoid organs/tissues
Red bone marrow
- all lymphocytes stem cells arise here
- site of B lymphocyte proliferation (mitosis) maturation
Thymus gland
- early in development (fetal stage) lymphocyte stem cells migrate here
- site of T lymphocyte proliferation (mitosis) and maturation
Secondary lymphoid organs and tissues
- where lymphocytes detect and remove pathogens
- locations where lymphocytes are activated and proliferate further
Secondary lymphoid organs and tissues include
- Lymph nodes
- Spleen
- Mucosal associated lymphoid tissue (MALT)
What are lymph nodes
Small masses of lymphoid tissue along lymphatic collecting vessels
Where are high concentrations of lymph nodes located
- cervical (neck)
- axillary (armpit)
- inguinal (groin)
- intestinal
- pelvic regions
Where is the spleen located
In the left side of abdominal cavity just below diaphragm next to stomach
