Unit 3 - Cellular Level Of Organization Flashcards

1
Q

The cell

A
  • basic structural and functional unit of the body
  • can perform all basic life functions
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2
Q

Principal parts of the cell

A
  1. Cell membrane/plasma membrane/plasmalemma
  2. Cytoplasm (contains cytosol and organelles)
  3. Nucleus
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3
Q

Cell membrane

A

Boundary between the inside and outside of a cell

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4
Q

What is the cell membrane composed of

A
  1. Phospholipid bilayer
  2. Cholesterol
  3. Membrane proteins
  4. Membrane carbohydrates
  5. Microvilli
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5
Q

Phospholipid bilayer

A
  1. Phosphate head group (hydrophilic) (polar)
  2. FA tails (hydrophobic) (non-polar)
  3. Divides ICF (intracellular fluid) and ECF (extracellular fluid)
    - main component is water
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6
Q

Cholesterol

A
  • scattered throughout membrane
  • adds stability to the cell membrane
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7
Q

Integral (transport) membrane proteins

A
  • can completely pass through membrane but doesn’t always
  • integrated within the membrane, therefore have a hydrophobic region
  • some extend across entire membrane, and are called transmembrane proteins
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8
Q

Peripheral membrane proteins

A
  • can face inside or outside of cell
  • attached to either surface of integral proteins (on the periphery of the cell membrane)
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9
Q

Functions of membrane proteins

A
  • enzymes
  • transporters (help transport molecules in and out of cell) (ATP is required)
  • channels (ATP is not required)
  • receptors (tell the cell what to do)
  • anchors (needs to be anchored to a certain region of the body)
  • identity markers (for immune system)
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10
Q

Where are membrane carbohydrates found

A

Only on outer surfaces

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11
Q

What are membrane carbohydrates bound to

A

Proteins (glycoproteins) or lipids (glycolipids)

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12
Q

Function of membrane carbohydrates

A
  1. Cell recognition (spem recognizes egg)
  2. Anchor cells together
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13
Q

What is microvilli

A

Small projections of cell membrane

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14
Q

Function of microvilli

A

To increase surface area

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15
Q

Where is microvilli found

A
  1. Kidneys
    - increased surface area allows more waste to be absorbed
  2. Small intestine
    - increased surface area allows us to absorb more nutrients
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16
Q

What makes up the fluid mosaic model of the cell membrane

A
  1. Phospholipid bilayer
  2. Membrane proteins
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17
Q

Fluid mosaic model of cell membrane

A
  1. Fluid - membrane constitutions can move around (phospholipids and some proteins)
  2. Mosaic - proteins dot surface, like tiles in a mosaic
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18
Q

What is cytoplasm

A
  • area between the inside of the cell membrane and the outside of the nucleus
  • consists of cytosol and organelles
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19
Q

Cytosol

A
  • gel-like intracellular fluid
  • contains water, ions, and a suspension of carbohydrates, proteins and lipids
  • may contain inclusions (ex. Melanin and glycogen)
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20
Q

Organelles

A
  • structures that preform a specific function and are essential for life
  • can be:
    1. Non-membranous- in direct contact with cytosol
    2. Membranous- surrounded by membrane that isolates them from cytosol
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21
Q

Cytoplasm analogy

A

Jelly cake
- cytosol = jello
- organelles = fruit

22
Q

Non-membranous organelles

A
  1. Ribosomes
  2. Centrosomes
  3. Cytoskeleton
23
Q

Ribosome function

A
  • site for protein synthesis
24
Q

What do ribosomes contain

A
  • ribosomal RNA (rRNA)
  • proteins
25
Types of ribosomes
1. Free ribosomes - float in cytosol and make proteins that go to cytosol, mitochondria, and/or nucleus 2. Attached to endoplasmic reticulum (ER) - make proteins destined for all other sites
26
What are Centrosomes
Organizing centres for microtubules 1. Spindle apparatus (for cell division) 2. Organizes cytoskeleton
27
What do Centrosomes consist of
2 components: - a pair of centrioles - pericentriolar matrix
28
Function of cytoskeleton
- all types are used for structural support (cell shape) and are formed from proteins - important in cell movement, cell division, movement/anchoring or organelles and proteins
29
Types of cytoskeleton
1. Microfiliaments 2. Intermediate filaments 3. Microtubules
30
What are microfilaments made of
Actin (protein)
31
Function of microfilaments
- muscle contraction (with myosin) - cell locomotion - cytokinesis (separating cytoplasm into 2 cells)
32
Composition of intermediate filaments
Tissue specific - ex. Keratin (protein)
33
Microtubules
- hollow tubes made of tubulin (protein)
34
Function of microtubules
- Form: 1. centrioles 2. spindle apparatus 3. cilia (short) 4. flagella (long - move or secure organelles in place - also found in sperm
35
Membranous organelles
1. Mitochondria 2. Endoplasmic reticulum 3. Golgi apparatus/complex 4. Lysosomes 5. Nucleus
36
Mitochondria
- site of ATP synthesis - has a double membrane (inner and outer)
37
What does the mitochondria contain
- DNA - RNA - Proteins
38
Endoplasmic reticulum
- membranous network throughout cytoplasm
39
Rough ER
- lysosomes attached - synthesis of secretory, lysosomal and membrane proteins
40
Smooth ER
- lacks attached ribosomes - continuous with rough ER - synthesizes lipids and steroid hormones
41
Golgi apparatus/complex
- stacks of membrane discs - modifies proteins (trims or adds carbs to lipids) - sorts, packages and delivers proteins to cell membrane, lysosomes or for secretion
42
Golgi apparatus/complex analogy
Cellular post office
43
Lysosomes
- filled with digestive enzymes - digest bacteria, viruses, worn out organelles - clean up function
44
Lysosomes analogy
Lysol (cleans)
45
Nucleus
- largest membranous organelle - cell control Center - cells may have one or more nuclei
46
Parts of nucleus
1. Nuclear envelope 2. Nucleolus 3. Chromosomes/chromatid
47
Nuclear envelope
- covers nucleus - double membrane with nuclear pores that information passes through (inner and outer) - connected to ER
48
Nucleolus
- more than 1 in some plants - inside nucleus - non-membranous - dense (less light gets through) region of DNA, RNA and proteins where ribosomes are made and assembled
49
What do Chromosomes/chromatid contain
- DNA - Histone proteins (DNA is wrapped around the histone protein)
50
Dispersed chromosomes/chromatid
= chromatin - DNA uncoiled and not individually visible - in this form MOST of the time (when cell is not dividing)
51
Where is condensed and individually visible chromosomes/chromatid found
In dividing cells - during mitosis and meiosis