Unit 20 Flashcards

(37 cards)

1
Q

Where is Vitamin D produced?

A

The skin when it is exposed to UV light

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2
Q

History of Vitamin D

A

1880-1920, 90% of kids in Europe and Boston had rickets

Industrialization –> coal burning –> pollution –> no exposure to UV

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3
Q

When do symptoms of rickets disappear

A

When exposed to UV

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4
Q

History of Thiamin

A

Beri Beri; 1st medical link to dietary deficiency.

Made by japanese doctor who observed a navy crew who only ate rice.

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5
Q

Lack of Thiamin

A

Lethargy, fatigue, complications affecting the cardiovascular system, the nervous system, muscular and GI

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6
Q

History of Niacin

A

Pellegra:
The three D’s = Diarrhea, dementia, and dermatitis.

Corn was a staple, but it kept going bad. So they removed the germ to prevent but stripped the niacin with it.

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7
Q

Vitamin A Deficiency

A
  • night blindness
  • can progress to permanent blindness
  • Africa and SE Asia = high prevalence
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8
Q

Vitamin A (where can you get it from)

A

Beta-Carotene (precursor or pro-vitamin to retinol)

Retinol (actual Vitamin A)

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9
Q

Beta-Carotene

A

Precursor or pro-vitamin to retinol

  • comes from plants
  • dark green vegetables
  • deep orange fruits
  • comes from plant sources

Can risk the skin turning a yellow/orangish colour

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10
Q

Retinol

A

Actual Vitamin A

  • Animal product with fat
  • forms of retinol used in some acne medications
  • more risks of toxicity in comparison to beta-carotene
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11
Q

Goiter

A

Iodine Deficiency

-leads to hypothyroidism (inability to tolerate cold, weight gain, fatigue)

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12
Q

Iodine Deficiency

A

Goiter
Leads to hypothyroidism (under-functioning)

being deficient in iodine, thyroxine decreases, thyroids start to become overactive

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13
Q

What are the two water soluble vitamins?

A

Vitamin B and C

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14
Q

Water Soluble Vitamins

A

Vitamin B, C
They will dissolve in water.

They “wash out” of the body in one to several days (if there is too much)

EXCEPT Vitamin B12 - it can be stored up to one year in the liver

Because it can wash out excess, does not make it safe in high doses. “megadoses”

These vitamins are easily destroyed during food storage and prep.

Because they are water soluble they are susceptible to oxidation

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15
Q

4 ways to minimize nutrient losses in fruits and vegetables

A
  1. Refrigerate
  2. to minimize oxidation, reduce contact with air
  3. wash before cutting
  4. steam or stir-fry, avoid high temps for long time
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16
Q

Folate

A

AKA. Folacin or Folic Acid

Critical vitamin
Mostly get it from vegetables
synthetic available bioavailable than food folate

17
Q

Where can you get Folate

A

Most Vegetables

  • leafy green vegetables
  • legumes
  • liver
  • lentils
  • fortified grains

Most common is enriched or fortified products

18
Q

Lack of Folate in DNA

A

Reduces DNA stability

  • induces and accelerates carcinogenesis
  • structure of cells genetics become disrupted –> abnormalities –> cancer
19
Q

Lack of Folate for Heart

A

-homocysteine accumulates in blood – heart attacks, strokes

20
Q

Lack of Folate: Fetal Health

A
  • almost complete absence of spinal cord

- brain deformities

21
Q

How much folate needs to be consumed by Females? Normal and pregnant

A

400 ug = all females

600 ug = pregnant females

22
Q

Vitamin C:

A
  1. Antioxidant
  2. Cofactor in collagen formation
  3. Cofactor in other reactions
  4. In stress
  5. Common Cold
23
Q

Vitamin C: Antioxidant

A

Protects tissues from oxidative stress

24
Q

Vitamin C: Cofactor in Collagen formation

A
  • helps form collagen (fibrous structural protein of connective tissues)
  • assists in preventing bruising

Hemorrhaging or bleeding = major symptom with vitamin deficiency

25
Vitamin C: Cofactor in other reactions
- conversion of tryptophan = serotonin + norepinephrine - fatty acid transport into mitochondria for energy metabolism - making of hormone
26
Vitamin C: In Stress
adrenal glands hold the most vitamin c Released when stressed
27
Vitamin C: Common COld
1 g/day = 1 day shorter cold & reduced severity of symptoms (by 23%) - reduces histamine - strong placebo effect
28
How much Vitamin C to prevent Scurvy
10 mg 100mg saturate body pool of vitamin C
29
How much vitamin C for females and males
Females: 75 mg/day Males: 90 mg/day
30
Vitamin C Cons
- interferes with urine test in detecting diabetes | - dangerous for people with iron overload in blood (hemochromatosis) - inflammatory
31
Hemochromatosis
Iron overload in blood Vitamin C can be dangerous -- inflammatory
32
Vitamin D: Bone Growth
- raises blood concentrations of Calcium and phosphorous - INC absorption from intestine - INC reabsorption from kidneys *mobilization from bones into blood
33
Vitamin D: Cancer
Recent research that increased vitamin D lowers breast, prostate and colon cancer
34
Vitamin D: Multiple Sclerosis; Rheumatoid arthritis
- living higher than 37 degrees lat. INC MS Risk | - 400 IU supplement decreases the risk by 40%
35
Vitamin D: Synthesis & Activation
In the skin we synthesize it (Inactive form) --> goes to liver --> kidnets for transformation/processing. Outside of the liver we have an active form of vitamin D 10-15 minutes sunlight (dark skin up to 3 hrs) - Fluid milks (reliable source) - Fortified dairy, margarine, fish oils, egg yolk, endogenous products
36
Vitamin D: reduced production
- 70 years old; only 30% - institutionalized people at higher risk - sunscreen reduces absorption
37
Mushrooms and Vitamin D
Mushrooms that have been exposed to ultraviolet light INCREASES vitamin D 400 IUs per serving