Untitled Deck 1

Question 1

Adrenaline acts on which receptors?

Answer 1

a1,2, b1,2

Question 2

Adrenaline causes vasoconstriction on what receptor?

Answer 2

A1

Question 3

What is the main path of coagulation?

Answer 3

extrinsic pathway

Question 4

Which factor activation is inhibited by heparin?

Answer 4

factors 2,9,10,11

Question 5

Where do both coagulation pathways meet?

Answer 5

in factor 10 activation

Question 6

What is the role of thrombin?

Answer 6

converts fibrinogen to fibrin

Question 7

What is fibrinolysis?

Answer 7

plasminogen converted into plasmin to break down fibrin

Question 8

What is the cardiac index formula?

Answer 8

Cardiac index = Cardiac output / body surface area.

Question 9

What is the role of angiotensin II?

Answer 9

vasoconstriction

Question 10

What is atropine’s action?

Answer 10

Muscarinic receptor antagonist (inhibits parasympathetic action)

Question 11

What are examples of TNF alpha inhibitors?

Answer 11

infliximab, adalimumab, etanercept

(RA and Chrons)

Question 12

What are examples of anti-VEGF drugs?

Answer 12

Bevacizumab

(colorectal cancer)

Question 13

What is an example of a HER receptor drug?

Answer 13

Transtuzumab

(breast cancer)

Question 14

What is an example of an IL2 binding drug?

Answer 14

Basiliximab

(renal transplant)

Question 15

What is the use of cetuximab?

Answer 15

Colorectal cancer

Question 16

What is the ERCP prep?

Answer 16

clotting check, ABx, vit K if jaundiced

Question 17

What is the OGD prep?

Answer 17

NBM for 6h

Question 18

What is the flexible sigmoidoscopy prep?

Answer 18

Phosphate enema 30min pre procedure

Question 19

What is the colonoscopy prep?

Answer 19

check U&E, if normal then oral purgatives

Question 20

What is the lignocaine dose/adrenaline?

Answer 20

3mg/kg / 7mg/kg

Question 21

What is the bupivacaine dose/adrenaline?

Answer 21

2mg/kg both

Question 22

What is the prilocaine dose/adrenaline?

Answer 22

6mg/kg / 8mg/kg

Question 23

What is an acute dystonic reaction?

Answer 23

resting tremor, bradykinesia, involuntary spasm movements

Question 24

What is the cause of an acute dystonic reaction?

Answer 24

antidopaminergic drug such as metoclopramide

Question 25

What is the treatment for an acute dystonic reaction?

Answer 25

benzhexol or procyclidine

Question 26

What are complications of colorectal surgery?

Answer 26

infection, bleeding, anastomotic leak

Question 27

What does cryoprecipitate contain?

Answer 27

factor 8, factor 13, vWF, fibrinogen

Question 28

mid point of inguinal ligament

Answer 28

asis to pubic tubercle half way (this is the deep ring)

Question 29

mid inguinal point

Answer 29

asis to pubic symphysis - surface marking of femoral pulse

Question 30

tetraology of fallot

Answer 30

- ventricular septal defect - pulmonary stenosis - right ventricular hypertrophy - overriding aorta

Question 31

superficial partial thickness burn

Answer 31

moist erythematous blistering blanching

Question 32

SUFE

Answer 32

obese

Question 33

Perthes

Answer 33

boys 4-8yo, (boys with low birth weight and ADHD)