Untitled Deck 3 Flashcards

1
Q

Dysphasia lusoria?

A

Compression of oesophagus due to aberrant right subclavian artery

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2
Q

BRCA1?

A

Chromosome 17

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3
Q

BRCA2?

A

Chromosome 13

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4
Q

Small cell lung cancer?

A

In smokers

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5
Q

Adenocarcinoma of the lung?

A

Most common in never smokers

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6
Q

Upper PSA limit?

A

(age-20)/10

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7
Q

Takayasu arteritis?

A

Large vessel granulomatous vasculitis

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8
Q

Buerger’s disease?

A

Segmental thrombotic occlusions of small and medium sized vessels

Corkscrew shaped collateral vessels seen

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9
Q

Leriche syndrome?

A

Atheromatous disease of iliac vessels

Buttock claudication and impotence

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10
Q

Primary sclerosing cholangitis is a risk factor for?

A

Cholangiocarcinoma

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11
Q

Marfan syndrome?

A

AD, defect in fibrillin gene on chromosome 15

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12
Q

Mirel scoring?

A

Stratifies risk of fracture for bone metastasis

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13
Q

Odynophagia?

A

Painful swallowing

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14
Q

Oncogenes?

A

sis, myc, RET, Src, Ras

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15
Q

Hodgkin lymphoma?

A

Reed Sternberg cells (2 nuclei)

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16
Q

Ann Arbor staging system?

A

For staging of Hodgkin lymphoma

Nodes on one or both sides of the diaphragm

17
Q

MEN type 1 most common presentation?

A

Hypercalcemia

18
Q

MEN 1 3Ps?

A

Parathyroid, pancreas, pituitary

19
Q

MEN 1 gene?

A

MENIN gene chromosome 11

20
Q

MEN 2 and 3 gene?

A

RET gene chromosome 10

21
Q

Wallerian degeneration?

A

Axonal degeneration distal to the site of surgery

22
Q

Axonotmesis?

A

Axon damaged, myelin sheath preserved

23
Q

Neurotmesis?

A

Axon and myelin sheath damaged

24
Q

Metaplasia?

A

Cell type conversion

25
Why the different position of recurrent laryngeal n on both sides?
Due to aortic arches V and VI disappearing on the right ## Footnote Loops under right subclavian vs on the left loops under VI/ligamentum arteriosum
26
Superior laryngeal n?
Innervates cricothyroid, high pitch and singing
27
Inferior laryngeal n?
Innervates intrinsic larynx muscles, vocal cords, speech, swallowing
28
Trachea lining
Lined by ciliated columnar epithelium
29
PT?
Vitamin K dependent factors 2, 7, 9, 10
30
APTT?
Factors 8, 9, 11, 12
31
Jaundice and vit K?
Impairs production of Vitamin K