Upper GI Flashcards

1
Q

Post Gastectomy complications

A

Rapid emptying of food from stomach into the duodenum: diarrhoea, abdominal pain, hypoglycaemia
Complications: Vitamin B12 and iron malabsorption, osteoporosis
Treatment: High protein, low carbohydrate diet. Replace B12/Fe/Ca

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2
Q

Dieulafoy lesion

A

These small arterial lesions are a rare cause of bleeding and are characterised by a single large tortuous arteriole in the sub mucosa.

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3
Q

Feeding in CVA with unsafe swallow

A

PEG

Will be jejenostomy if oesophagectomy

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4
Q

Tx of 50yo with Barretts oesophagus is diagnosed with high grade dysplasia on recent endoscopy. The lesions are multifocal and mainly distally sited

A

Oesophgectomy

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5
Q

Tx of Barrets with dysplasia in elderly with localised lesion

A

Endoscopic mucosal resection

Low grade dysplasia in conjunction with Barretts oesphagus should be monitored with regular (6 monthly) upper GI endoscopy and quadrantic biopsies. If the disease remains static at 2 years then the screening frequency may be decreased.

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6
Q

Ivor Lewis procedure

A

Combined laparotomy and right thoracotomy
Laparotomy To mobilize the stomach
The greater omentum is incised away from its attachment to the right gastroepiploic vessels
The left gastric vessels are then ligated,

Right Thoracotomy Oesophageal resection and oesophagogastric anastomosis
Through 5th intercostal space

Indication
Lower and middle third oesophageal tumours

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7
Q

Acute vs chronic ulcer on endoscopy

A

Acute- small and no fibrosis
Chronic- large and fibroses

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8
Q

Proximal Oesophageal SCC mx

A

managed with radical chemoradiotherapy

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9
Q

Mx of oesophageal cancer if distant disease

A

Palliate with metallic stent

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10
Q

Cholestatic picture with HIV dx

A

HIV is sclerosing cholangitis due to infections such as CMV, Cryptosporidium and Microsporidia

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11
Q

Iatrogenic perforations of the oesophagus management

A

TPN
This usually involves a nil by mouth regime, tube thoracostomy may be needed. Total parenteral nutrition is the safest option.

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12
Q

Mx of UGI bleeds

A

Admission to hospital careful monitoring, cross match blood, check FBC, LFTs, U+E and Clotting (as a minimum)

Patients with on-going bleeding and haemodynamic instability are likely to require O negative blood pending cross matched blood

Patients with suspected varices should receive terlipressin prior to endoscopy

Ideally all should undergo Upper GI endoscopy within 24 hours of admission.

Varices should be banded or subjected to sclerotherapy.
If this is not possible owing to active bleeding then a Sengstaken- Blakemore tube (or Minnesota tube) should be inserted. This should be done with care; gastric balloon should be inflated first and oesophageal balloon second.

Remember the balloon will need deflating after 12 hours (ideally sooner) to prevent necrosis. Portal pressure should be lowered by combination of medical therapy +/- TIPSS.

Patients with erosive oesophagitis / gastritis should receive a proton pump inhibitor.

Mallory Weiss tears will typically resolve spontaneously

Identifiable bleeding points should receive combination therapy of injection of adrenaline and either a thermal or mechanical treatment.

All who have received intervention should receive a continuous infusion of a proton pump inhibitor (IV omeprazole for 72 hours) to reduce the re-bleeding rate.

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13
Q

Cellular origin of pancreatic tumours

A

Ductal epithelium

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14
Q

Gastrinoma most common locatin

A

Duodenum

Most commonly found in the duodenum (in up to 50% patients), then the pancreas (approximately 20%)

Within triangle
-junction of common and cystic BD, junction of 2nd/3rd part od duodenum, junction of body and neck of pancreas

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15
Q

Epigastric discomfort and episodes of migratory thrombophlebitis. On examination he is mildly jaundiced

A

Adenocarcinoma of the pancreas

Trousseau’s sign: migratory superficial thrombophlebitis

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16
Q

What is usually divided during an Ivor Lewis Oesophagectomy

A

Azygous vein

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17
Q

Mx of bleeding duodenal ulcer on endoscopy

A

Inject adrenaline

+/- clips

Following these interventions patients should receive a proton pump inhibitor infusion. Those who re-bleed, may require surgery.

18
Q

Types of bariatric surgery

A

Gastric banding: band applied to upper stomach which can be inflated or deflated with normal saline. This affects satiety. Over a 5 year period complications requiring further surgery occur in up to 15% cases.

Roux-en-Y gastric bypass: a gastric pouch is formed and connected to the jejunum. Patients achieve greater and more longterm weight loss than gastric banding.

Sleeve gastrectomy: body and fundus resected to leave a small section of stomach

Biliopancreatic diversion +/- duodenal switch: bypass the small bowel. Greatest weight loss but a very complex procedure associated with malnutrition and diarrhoea.

Vertical banded gastroplasty (stomach stapling): rarely performed due to longterm failure rate.

Gastric balloon- highest failure rate- really only suitable as a bridge to a more definitive surgical solution.

19
Q

Where is zinc absorbed

A

Duodenum and jujenum

20
Q

Metastatic pancreatic cancer with jaundice tx

A

Endoscopic stent and palliative chemo

If no obstruction- palliative chemo

21
Q

Low grade dysplastic Barrets mx

A

Monitored with regular (6 monthly) upper GI endoscopy and quadrantic biopsies.

If the disease remains static at 2 years then the screening frequency may be decreased.

22
Q

Achalasia and mass in proximal oesophagus

A

Squamous CC

Achalasia is a RF

23
Q

Rockall score

A

ABCDE
A: Age
B: Blood pressure drop (Shock)
C: Co-morbidity - i.e score 2 for Major organ disease e.g. IHD, CCF, 3 for Renal or liver failure, metastatic cancer
D: Diagnosis - 0 MW, 2 for gastric cancer
E: Evidence of bleeding

24
Q

5w history of dysphagia, Barrett and food on endoscopy

A

Adenocarcinoma

25
Q

A 38 year old woman undergoes a gastric bypass procedure. Post operatively she attends the clinic and complains that following a meal she develops dizziness and develops crampy abdominal pain. What is the most likely underlying explanation?

A

Dumping syndrome, which can be divided into early and late, may occur following gastric surgery. It occurs as a result of a hyperosmolar load rapidly entering the proximal jejunum. Osmosis drags water into the lumen, this results in lumen distension (pain) and then diarrhoea. Excessive insulin release also occurs and results in hypoglycaemic symptoms.

26
Q

Dysphagia that is episodic and varies between solids and liquids

A

More likely motility disorder

27
Q

Bleeding ulcer- originally managed through adrenaline injection in endoscopy- suddenly tachy and hypo- mx?

A

Laparotomy and under running of ulcer

28
Q

Criteria for bariatric surgery

A

BMI >/= 40 kg/m2 or between 35-40 kg/m2 and other significant disease

Trialled conservative measures for 6 months.

Will receive intensive specialist management

They are generally fit for anaesthesia and surgery

They commit to the need for long-term follow-up

29
Q

Difficult OGD with noted surgical emphysema after

A

Pharyngeal pouch

30
Q

Which bariatric surgery associated with delayed gastric emptying and which has the best function

A

Anterior gastrojejunostomy- worst

Roux en Y- best

31
Q

Young adult with recurrent ulcerations- diagnosis and blood results

A

MEN1- zollinger Ellison

Gastrin

32
Q

Where mineral/vitamin absorption occurs

A

Iron- duodenum
Folate- jejunum
B12- terminal ileum

33
Q

Anterior vs posterior duodenal ulcer presentation

A

Anteriorly sited ulcers may perforate and result in peritonitis

Posteriorly sited ulcers may erode the gastroduodenal artery and present with haematemesis and/ or malaena.

34
Q

Diagnosis of barrels on histology

A

Metaplasia to columnar cells with goblets

35
Q

Mx of insulinoma of head of panc

A

Enucleation of lesion

36
Q

Complication of re fundoplication

A

Damage to vagus nerve

If both are damaged, there will be delay to gastric emptying.

37
Q

Which bariatric surgery has the highest failure rates

A

Gastric balloon

38
Q

Most common location of gastronome

A

Duodenum
Then pancreas

39
Q

Management of upper oesophageal cancer

A

Radio and chemo

40
Q

Post oesophagectomy, chest pain, bubbling in chest drain

A

Air leak from lung

41
Q

Another sign for achalasia on Barium swallow

A

Rats tail