Urinary System 2: Ureters, Bladder, & Urethra Flashcards

(65 cards)

1
Q

PCT is the 1st

A

segment of the renal tubule

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2
Q

Where Does the PCT begin?

A

at the urinary pole of the glomerulus

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3
Q

Where does a majority of glomerular flitrate get resorbed?

A

PCT

70%

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4
Q

PCT is very very

A

convoluted

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5
Q

what are the name in order of the parts of the Loop of Henle?

A
  • Pars recrta (thick)
  • thin descending
  • thin ascending
  • thick ascending limb
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6
Q

The thin portion of the loop of Henle has

A

squamous epithieum

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7
Q

The thick parts of the Loop of henle has

A

cubodial epitheilum

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8
Q

What wraps around the loop of henle?

A

Vasa recta

is parallel to

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9
Q

Loope of henle serves to create

A

high osmotic pressure in the renal
medulla

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10
Q

The loop of Henle creates high osmotic pressure in the renal medulla via the

A

counter-current multiplier system

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11
Q

The loop of henle counter-current multiplier system hel to create

A

hypertonic urine

excretion of excess solute

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12
Q

The bulk of the loop of henle extends into the

A

medula

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13
Q

In juxtamedullar nephorns thin limbs are

A

long

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14
Q

in cortical neprhons thin limbs are

A

short

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15
Q

Pars recta has a

A

brush border

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16
Q

There is a _________ extracellular Na in the medulla

A

higher

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17
Q

Countercurrent multiplier funciton is to

A

to generate high osmotic pressure in ECF of renal medulla

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18
Q

How does the Countercurrent multiplier generate hgih osmotic pressue inthe ECF

A

via Na-K pump in thick acsending

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19
Q

The vasa recta arises form

A

efferent arterioles of
juxtamedullary
nephrons

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20
Q

Distal convoluted tubule continuation of

A

thick ascending
limb of Loop of Henle

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21
Q

Where is the DCT located

A

in the cortex

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22
Q

DCT has cuboidal epithelium but

A

lacks brush border

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23
Q

DCT is Responsible for

A
  • active resorption of Na & Cl
  • coupled with secretion of H & K ions
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24
Q

What are the two cell types of the DCT?

A
  • prinicpal cells
  • intercalated cells
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25
prinicpal cells resorb
Na & water
26
prinicpal cells secrete
K
27
intercalated cells mediate secretion of
H + and HCO3 −
28
intercalated cells mediate reabsorption
Cl − and K+
29
What is important Regulators of Acid- Base Balance
intercalated cells
30
intercalated cells are important
Regulators of Acid- Base Balance
31
prinicpal cells and intercalated cells are controled by
aldosterone | adrenal mineralocorticoid
32
JGA stands for
juxtaglomerular apparatus
33
Juxtaglomerular apparatus is combined
* baroreceptor (pressure) * chemoreceptor ([ion]
34
Juxtaglomerular apparatus regulates
blood pressure
35
Juxtaglomerular apparatus regualtes blood pressure via
renin-angiotensin-aldosterone system (RAAS)
36
parts of the renin-angiotensin-aldosterone system (RAAS)
1. macula densa 2. juxtaglomerular cells 3. extraglomerular mesangial cells
37
Macula densa __________ sensitive to changes in ________in filtrate.
Chemoreceptor; Na
38
Macula densa are found in
side of distal convoluted tubule
39
Juxtaglomerular cell are found in
wall of afferent arteriol
40
Juxtaglomerular cells Act as _________; detect changes in _______
baroreceptors; blood pressure
41
Juxtaglomerular cells produce ______ in response to low BP
renin | decrease Blood volume
42
Renin converts
angiotensinogen to angiotensin
43
Extraglomerular mesangial cells are found
surrounding afferent and efferent arteriole
44
Extraglomerular mesangial cells fucntion
unclear; provide structural support & phagocytosi
45
Extraglomerular mesangial cells may assist in
tubular glomerular feedback | info from macula densa to intraglomerular mesangial cell
46
What watch if the BP is low
* Macula Densa * Juxtaglomerular
47
intraglomerular mesangial cells | function
contraction/relaxation may change glomerular filtration rate
48
Macula densa acts as sensor, regulating
juxtaglomerular function by monitoring Na+ & Cl- levels in the DCT
49
Angiotensinogen is converted to
active angiotensin 1 | by renin
50
Angiotensin causes
suprarenal glands to secrete aldosterone
51
What converts Angiotensin 1 to 2
ACE | Angiotensin Converting Enzyme
52
ACE inhibitors helop to treat
hypertesnion (high blood pressure)
53
DCT dumps into
collecting tubules | isotonic urine
54
Collecting tubules dump into
collecting ducts | isotonic urine
55
Collecting duct leave
cortex and enters medulla all the way down to the papilla
56
Collecting Ducts play an important role in
final concentration of urine | interstitium & vasa recta
57
ADH causes collecting ducts to
increase the number of aquaporins in their walls
58
Epithelium responsive to
antidiuretic hormone (ADH, Vasopressin)
59
antidiuretic hormone is released by
posterior pituitary
60
ADH cause
water to be lost from ducts | hypertonic urine
61
Without ADH
ducts remain impermeable to water | iso-/hypotonic urine
62
Mutations to AQP-2
do not respond to ADH | in diabetes
63
After reaching the papilla what is the order that urine travels?
minor calyces major calyces renal pelvis ureter
64
Ureter lined by
transitional epithelium
65
Urinary Bladder lined by
Urothelium (transistental) ballon surface | Stratified