Vagina Pathology

Question 1

Septate vaginae form because _____

Answer 1

Mullerian ducts fail to fuse

Question 2

Septate vaginae can occur to to intrauterine exposure to _____

Answer 2

DES

Question 3

Sx’s = red, granular areas that stand out from surrounding normal pale-pink vaginal mucosa

Answer 3

Vaginal adenosis

Question 4

Lesions on the lateral walls of the vagina that are d/t Wolffian duct dysfunction

Answer 4

Gartner duct cysts

Question 5

Lesions in the proximal vagina that are derived from mullerian epithelium

Answer 5

Mucus cysts

Question 6

VaIN is associated with which cancer and which pathogen?

Answer 6

SCC (HPV)

Question 7

What is the greatest risk factor for VaIN and SCC of the vagina?

Answer 7

Previous carcinoma of the cervix/vagina

Question 8

What area of the vagina does VaIN and SCC affect?

Answer 8

Posterior wall at the junction with the ectocervix

Question 9

Sx’s = polypoid, bulky mass looking like cluster of grapes protruding from vagina in a child < 5 yo

Answer 9

Embryonal Rhabdomyosarcoma (Sarcoma Botryoides)

Question 10

Morph: small tumor cells with oval nuclei and protrusions of cytoplasm from one end resembling a tennis racket

Answer 10

Embryonal Rhabdomyosarcoma