Vascular Disease Pathology Flashcards Preview

Cardio 2 > Vascular Disease Pathology > Flashcards

Flashcards in Vascular Disease Pathology Deck (17):
1

2 Forms of Arteriosclerosis (& apperance)

Hyaline arteriosclerosis (benign hypertension), pink hyaline ring around vessel
Hyperplastic Arteriosclerosis (malignant HTN), onion skin around vessel bc involves basement membrane

2

2 Kinds of Aneurysms

True Aneurysm: intarct attenuated arterial/ventricular wall
False Aneurysm: defect in vascular wall leading to extravascular hematoma that freely communicates w/ intravascular space

3

2 Shapes of Aneurysms and Major Point

Saccular/Berry - balloon style, all walls enlarged
Fusiform: one side of vessel enlarged

4

Lines of Zahn

Diff substances in thrombus building up in aneurysm

5

2 Main Predisposing Conditions for Aneurysm

Athersclerosis
HTN

6

3 Pathogenic Mechs of Aneurysms

Defect in connective tissue of vascular wall (Marfan's, Ehlors-Danlos)
Increased collagen degradation
Cystic medial degeneration - ischemic/deg changes resulting in loss of SM and elastic fibers w/ scarring and shit

7

Leading Cause of AAA vs. TAA

Artherosclerosis (degeneration of media) vs. HTN

8

Frequent Association w/ AAA

Mural thrombus

9

Syphilitic Aneurysms (3)

Almost always thoracic, ascending and transverse parts
Endarteritis of vasa vasorum, causing ischemic destruction of media
Stellate scars develop in media causing wrinkling - tree barking

10

Aortic Dissection (what it is and origin)

Blood splays apart laminar lanes of media forming a blood filled channel w/in aortic wall. Originiate w/ intima tears

11

Classifications of Aortic Dissections (2.3)

Type A - involves asc aorta. DeBakey I - only ascending, Debakey II - both asc and desc
Type B - does not involve asc aorta. DeBakey III - only desc

12

Aortic Dissection Clinical Presentation

Sudden onset of excruciating pain beginning in chest, radiating to back and moving downward as dissection progresses

13

Diagnosis for Immunologic Vasculitis

Antineutrophil cytoplasmic antibodies (ANCAs), can be c-ANCA or p-ANCA

14

Most Common AI Vasculitis

Temporal/Giant Cell Arteritis. Affects temporal region

15

Phlebothrombosis vs. Thrombophlebitis

Thrombosis of veins vs. Inflammation of veins

16

Lymphangitis Most Common Cause

GAS

17

Peau d'orange

Swelling of breast when lymphatics blocked by tumor emboli