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Cardio 2 > Embryo > Flashcards

Flashcards in Embryo Deck (14):
1

Primary Heart Field

Cells initially moving out of primitive streak. Form proximal, venous side of tube

2

Secondary Heart Field

Forms distal, arterial part of tube

3

Weeks 2, 3 and 4

2: 2 tubes
3: Tubes fused, form different general parts
4: Folding of heart

4

4 Parts of Tube (& part(s) that lead into it)

(Sinus venosus lead into->)
Primordial atrium
Ventricle
Bulbus cordis
Truncus arteriosus

5

Looping

Dextrofolding of heart, bends to R side in week 4

6

Weeks 4-7

Septation

7

2 Ostium and Septum

Ostium Primus first forms b/w 2 A, then covered by septum primum. Little holes join to form ostium secundum which will be partially covered by septum secundum to form oval foramen (septum secundum overlaps primum)

8

Holt Oram Syndrome

ASD and upper limb defects from Tbx5 gene mut

9

Double Inlet LV

When AV canal doesn't move to the R, so both AV valves open into LV

10

Why Have 3 and 2 Cusps for AV valves

AV canal originally has 5 leaflets, cushions come down and separate into 3 and 2

11

3 Components of Interventricular Septum (& remainder)

Muscular/trabecular ventricular septum
Outlet Septum (Conotruncal)
Inlet Septum (from endocardial cushions)
5% remaining is membranous septum where all 3 portions meet near base, can be a VSD here

12

Double Outlet RV

Conotruncal septum doesn't really form well so both A and P outflows from RV

13

Spiral Septum

Truncus sweelings twist around to form 2 duh (Right is Right in front and L is left behind)

14

3 Pharyngeal Arches Important for Heart

3 - 4 - 6 (pause) Ronak likes to suck - dicks. Hope that helps :)