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Flashcards in Changes at Birth Deck (10):
1

Umbilical Cord 4 Contents

2 Umbilical A.s (deox)
1 Umbilical V.
Wharton's Jelly (love lubing up with that shit knowhatimsayin?)

2

Ductus Venosus

Carries high oxygenated blood from umbilical vein to IVC. Kinda like gate for fetal circulation

3

Foramen Ovale

RA -> LA, bypass lungs so high O2 shit gets to brain and doesn't overload lungs

4

Ductus Arteriosus

Pulmonary a. -> aorta to protect lungs from circulatory overload

5

Ibuprofen

Can close DA

6

2 Important Things At Birth

Clamping Umbilical Cord - decrease umbilical flow, which constricts ductus venosus, decreases RAP, and resistance vessels chance to arterioles with much higher resistance so increase in SVR
First Cry/Breath - air expands lungs, decreasing PVR, decrease DA shunt, increase flow to lungs and return from lungs, so increase in LAP
Decrease in RAP and increase in LAP causes FO to close

7

3 Biochemical Changes at Birth

Increase in O2
Decrease in PGs
Increase in bradykinins

8

Oxygen in Newborn

Oxygen increases, which relaxes pulmonary smooth muscle and constricts DA and DV

9

Fetal Myocardium

Fewer sarcomeres and less efficient contractile function (variety of factors), so has to adjust chronotropically. Neonate is kinda in the middle

10

Persistent Pulmonary HTN of the Newborn (PPHN)

Persistent fetal circulation