vasculitis

Question 1

vasculitis is

Answer 1

inflammation of blood vessels

Question 2

__ are seen in blood vessel walls in vasculitis

Answer 2

leukocytes

Question 3

typical inflammation sxs

Answer 3

fever
myalgias
arthralgias
fatigue

Question 4

organ/disease specific sxs in vasculitis due to

Answer 4

vessel lumen narrows or occludes from inflammation

Question 5

large vessel vasculitis includes

Answer 5

temporal arteritis
takayasu’s arteritis

Question 6

medium vessel vasculitis includes

Answer 6

polyarteritis nodosa
kawasaki disease
buerger’s disease

Question 7

small vessel vasculitis includes

Answer 7

churg-strauss
Wegener’s granulomatosis
microscopic polyangitis
henoch-schonlein purpura

Question 8

purpura

Answer 8

red-purple skin lesions

Question 9

palpable purpura is due to

Answer 9

extravagtion of blood into skin (code for vasculitis)

Question 10

non palpable purpura is usually

Answer 10

noninflammatory

Question 11

vasculitis treatment

Answer 11

steroids or cyclophosphamide

Question 12

features of temporal arteritis

Answer 12

elderly female
HA

Question 13

features of takayasus

Answer 13

again female
pulseless

Question 14

features Kawasaki disease

Answer 14

asian child
red rash
strawberry tongue

Question 15

features buergers disease

Answer 15

smokers hands

Question 16

features of polyarteritis nodosa

Answer 16

hep b

Question 17

features of henoch-schonlein purpura

Answer 17

child
URI
melena

Question 18

features of charge strauss

Answer 18

asthma
eosinophils
p-ANCA

Question 19

features of Wegener’s granulomatosis

Answer 19

sinus
kidneys
lungs
c-ANCA

Question 20

microscopic polyangitis

Answer 20

kidneys
lungs
p-ANCA

Question 21

temporal arteritis narrowing of

Answer 21

temporal artery system

Question 22

sxs of temporal arteritis

Answer 22

HA
jaw claudication

Question 23

if temporal arteritis is not treated it can lead to

Answer 23

blindness

Question 24

diagnosis of temporal arteritis

Answer 24

biopsy of temporal artery (granulomas)

Question 25

treat temporal arteritis with

Answer 25

high dose steroids

Question 26

takayasu's arteritis is due to

Answer 26

granulomatous thickening of aortic arch and branches

Question 27

takayasu's arteritis classical sxs

Answer 27

weak pulses one arm

Question 28

kawasaki disease is due to

Answer 28

narrowing of proximal great vessels

Question 29

classic involvement of Kawasaki

Answer 29

skin lips tongue

Question 30

sxs of Kawasaki

Answer 30

red rash strawberry tongue

Question 31

feared complication of Kawasaki

Answer 31

coronary aneurysms (MI)

Question 32

treatment of Kawasaki

Answer 32

IV immunoglobulin and aspirin

Question 33

scarlet fever

Answer 33

fever sore throat*** sandpaper skin strawberry skin

Question 34

Reye's syndrome characterized by

Answer 34

encephalopathy liver failure fatty infiltration

Question 35

Reye's syndrome sxs

Answer 35

vomiting confusion seizures coma

Question 36

Reye's syndrome often follows

Answer 36

viral illness

Question 37

Reye's syndrome caused by

Answer 37

diffuse mitochondrial insult

Question 38

Reye's syndrome associated with

Answer 38

aspirin use in children

Question 39

buergers disease seen in

Answer 39

male smokers

Question 40

burgers disease is due to

Answer 40

poor blood flow to hands/feet

Question 41

treatment for buerger's disease

Answer 41

smoking cessation

Question 42

polyarteritis nodosa due to

Answer 42

immune complex mediated

Question 43

polyarteritis nodosa is what type of hypersensitivity

Answer 43

type III

Question 44

polyarteritis nodosa sxs

Answer 44

motor/sensory deficits nodules/purpura on skin renal failure

Question 45

polyarteritis classic case

Answer 45

hep B+ nerve deficits skin nodules purpura renal failure

Question 46

henoch-schonlein purpura is the mc

Answer 46

childhood systemic vasculitis

Question 47

henoch-schonlein purpura is associated with

Answer 47

IgA

Question 48

henoch-schonlein purpura sxs

Answer 48

palpable purpura on buttocks/legs abd pain, melena nephritis

Question 49

henoch-schonlein purpura classic cause

Answer 49

child with recent URI palpable purpura melena

Question 50

__ is best test for henoch-schonlein

Answer 50

tissue biopsy

Question 51

ANCA diseases

Answer 51

churg-strauss syndrome wegener's granulomatosis microscopic polyangiitis

Question 52

ANCA all have

Answer 52

pulmonary & renal involvement

Question 53

c-ANCA seen in

Answer 53

wegener's

Question 54

p-ANCA seen in

Answer 54

charge-strauss microscopic polyangitis

Question 55

churg-strauss sxs

Answer 55

asthma sinusitis neuropathy

Question 56

__ is seen in charge Strauss

Answer 56

eosinophilia

Question 57

wegener's granulomatosis ses

Answer 57

sinusitis, otitis media, hemoptysis

Question 58

renal sxs of wageners

Answer 58

hematuria red cell casts

Question 59

__ on biopsy of wegener's

Answer 59

granulomas

Question 60

microscopic polyangitis sxs

Answer 60

hemoptysis, kidney failure, purport

Question 61

microscopic polyangitis is just like wegeners except

Answer 61

no sinusitis P-anca no C-anca no granulomas

Question 62

good pastures syndrome due to

Answer 62

antibody to collagen

Question 63

sxs of good pasture syndrome

Answer 63

hemoptysis & nephritic syndrome

Question 64

classic cause of good pastures

Answer 64

young male hemoptysis hematuria

Question 65

biopsy of temporal arteritis reveals

Answer 65

multinucleated giant cells

Question 66

patients with polyarteritis nodosa present with

Answer 66

tender skin nodules

Question 67

fibrinoid necrosis is associated with

Answer 67

polyarteritis nodosa

Question 68

c-ANCA are antibodies against

Answer 68

proteinase-3

Question 69

p-ANCA are antibodies against

Answer 69

myeloperoxidase