Viral and Chlamydial Respiratory Tract Infections

Question 1

weakness/paralysis similar to poliovirus, non-polio enteroviruses and West nile virus =

Answer 1

acute flaccid myelitis

Question 2

What two syndromes are associated with complications of flu infection (other than pneumonia)

Answer 2

1. Reyes syndrome

2. Guillain-Barre syndrome

Question 3

Which form of chlamydiae is the infectious, nongrowing form responsible for dispersal

Answer 3

Elementary body

Question 4

What is the major form of transmission of rhinovirus?

Answer 4

hands = vector in person-to-person transmission

aerosol and fomites possible

Question 5

Which form of chlamydiae is the growing/vegetative form

Answer 5

reticulate body

Question 6

What make chlamydiae act like a virus?

What makes it act like a bacteria?

Answer 6

virus = energy parasite, obligate intracellular parasite 
bacteria = binary fission

Question 7

What are the two forms chlamydiae assumes

Answer 7

1. elementary body (spore like)

2. reticulate body (growing/vegetative form)

Question 8

antigenic subtypes of the flu are based on :

Answer 8

envelope proteins

Question 9

What is different about giving a flu vaccine to a child versus and adult

Answer 9

children under 9 need TWO ADMINISTRATIONS

Question 10

How long is immunity to rhinovirus?

What is this referred to as?

Answer 10

18 months

“transient” immunity

Question 11

What age group has the greatest incidence of rhinovirus in the winter

Answer 11

children and young adults

Question 12

What specifically happens during an antigenic drift of the influenza virus

Answer 12

point mutations of H or N proteins

Question 13

What is in a Quadrivalent form of a flu vaccine

Answer 13

2 type A viruses

2 type B viruses

Question 14

Why can the influenza virus go through antigenic shift and drift easily while other viruses cannot

Answer 14

segmented genome

Question 15

What is the major reservoir for flu virus

Answer 15

avian

Question 16

What specifically happens during an antigenic shift of the influenza virus

Answer 16

recombination involving entire genome segments encoding H or N gene

*implies mixed infections occur

Question 17

What is the #1 adverse effect of the flu vaccine

Answer 17

pain at the site of injection

Question 18

Which cells are more heavily infected with a cold (ARD)

Answer 18

cells lining nasal passage and pharynx

Question 19

The three types of flu (A, B, and C) are defined by:

Answer 19

nucleocapsid proteins

Question 20

What does the “N” stand for in naming flus

Answer 20

neuraminidase (viral penetration and release from infected cells)

Question 21

What does the “H” stand for in naming flus

Answer 21

H hemagglutinin (viral attachment)

Question 22

What are the four potential viruses associated with a cold (ARD)

Answer 22

rhinovirus
coronavirus
adenovirus
“unknown virus”

Question 23

How are flu vaccines grown

Answer 23

inside of embryonated chicken eggs

Question 24

What type of flu vaccine can you give to elderly patients to increase immune response

Answer 24

high potency and adjuvanated

Question 25

Which type of flu is the worst

Answer 25

type A

type B can also cause epidemics and C is weak

Question 26

Chlaymidae trachomatis can cause what respiratory infection

Answer 26

infant pneumonia

Question 27

Chlamydiae pneumonia is most associated with:

Answer 27

atherosclerosis

Question 28

Chlamydiae trachomatis in an infant usually goes to which type of tissue

Answer 28

ocular

Question 29

Regarding the flu, what is the thing that actually kills patients

Answer 29

secondary pneumonia

watch out for “Return of fever”
***he made a big point of this in the lecture and told us to “add it to our notes”