Tetanus and Botulism Flashcards

(49 cards)

1
Q

What form does the Amoeboid trophozoite of Naegleria fowleri arise from?

A

Flagellate trophozoites

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2
Q

What form does Naegleria fowleri take in VERY HARSH conditions

A

cyst

single nucleate

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3
Q

c. tetani or c. botulinum?

no fever

A

c. botulinum

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4
Q

Considered the most deadly substance ever

A

botulinum toxin type H

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5
Q

c. tetani or c. botulinum?

more neurotoxic

A

c. botulinum

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6
Q

c. tetani or c. botulinum?

toxin observed in fecal sample

A

c. botulinum

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7
Q

Which meningitis causing bacterium is an OBLIGATE ANAEROBE

A

clostridium species

c. tetani and c. botulinum

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8
Q

What form does Naegleria fowleri take when it needs to eat, have sex, and destroy things aka fuck shit up

A

Amoeboid trophozoites

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9
Q

What form does Naegleria fowleri take when there is a change in environment and it needs to get the hell outta there

A

Flagellate Trophozoite

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10
Q

Clearing zones on e. coli covered agar plates

A

Naegleria fowleri

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11
Q

c. tetani or c. botulinum?

subterminal spores

A

c. botulinum

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12
Q

c. tetani or c. botulinum?

lockjaw and trismus

A

c. tetani

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13
Q

c. tetani or c. botulinum?

food borne, honey in infants

A

c. botulinum

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14
Q

Toxoplasma gondii transmission

A

food borne****

zoonotic, congenital

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15
Q

What is the host for Toxoplasma gondii sexual stage

A

kitty kitty

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16
Q

c. tetani or c. botulinum?

risus sardonicus

A

c. tetani

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17
Q

c. tetani or c. botulinum?

fever

A

c. tetani

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18
Q

What is the infective stage of Naegleria fowleri

A

Flagellate trophozoites

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19
Q

c. tetani or c. botulinum?

toxin on chromosome – every bacteria will have toxins

A

c. botulinum

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20
Q

Can you get meningitis from drinking Naegleria fowleri in tap water?

A

no. destroyed in gastric juices

21
Q

cryptococcus neoformans transmission

A

inhaled for bird shit

NOT COMMUNICABLE

22
Q

c. tetani or c. botulinum?

toxin absorbed by local nerve endings, travels through blood and lymph

23
Q

How can we test for Toxoplasma gondii in preggos

A

PCR can detect parasite DNA in amniotic fluid

24
Q

Where is clostridium found?

A

normal intestinal flora
soil

basically everywhere

25
Diphenol oxidase | forms melanin from phenol containing substrates
cryptococcus neoformans
26
Naegleria fowleri infection results in:
primary acute meningoencephalitis (PAM) they die super quick
27
The only fungus that can cause meningitis
cryptococcus neoformans
28
Bird seed agar
cryptococcus neoformans
29
Negative India ink stain on a budding yeast
cryptococcus neoformans | ******************************
30
possible cause of SIDS
infant botulism
31
Toxoplasma gondii can cause severe complications in what kind of people
immunocompromised | newly infected preggos
32
Parasite causing meningitis
Toxoplasma gondii
33
approximately 70% of the cases of botulism infections occur in infants... why
no established gut flora
34
Protozoan that can lead to meningitis
Naegleria fowleri
35
How does Naegleria fowleri get to the brain
migrates along olfactory nerve to the brain (lobopodia) | unique sucker apparatus
36
c. tetani or c. botulinum? flaccid paralysis
c. botulinum
37
How does cryptococcus neoformans get into the brain
``` bird droppings ---> desiccated yeast cells ---> kicked up in the dirt and inhaled ---> infection ---> meningoencephalitis ```
38
Where does yeast prefer to go in the body
CSF
39
c. tetani or c. botulinum? toxin production is plasmid mediated-- not every bacteria will have toxins
c. tetani
40
Which stage of Toxoplasma gondii is infective?
cysts stage
41
c. tetani or c. botulinum? unopposed muscle contraction and spasm
c. tetani
42
clostridium gram (+/-) shape?
gram + | bacilli
43
c. tetani or c. botulinum? toxin prevents acetylcholine from being released
c. botulinum
44
c. tetani or c. botulinum? terminal spores with tennis racket appearance
c. tetani
45
cryptococcus neoformans presentation
asymptomatic or mimics the flu
46
Is cryptococcus neoformans a part of the normal flora?
no
47
c. tetani or c. botulinum? infection from trauma and entry of spores
c. tetani
48
Where is Naegleria fowleri found?
soil and fresh water lake havasu story that place is stupid anyway, don't go.
49
What is the triad of symptoms suggesting CONGENITAL toxoplasmosis
1. chorioretinitis 2. hydrocephalus 3. intracranial calcifications