WBC Flashcards
outline the innate immune cells
macrophage
granulocytes
dendritic cells
NK cells
what are the granulocytesq
neutrophils
eosinophils
basophils
mast cells
innate immunity
fast, non-sepecific, genertic body surfaces phagocytosis antimicrobial substances inflmation immunlogical surelance
adaptive immunity
antiegn specific
highly specalised
-B cells, T cells
leads to memory
lymphocytes
central role in immune system protecting against viral ifections
subdivisions of lymphocytes
Nk cells
B cells
T cells
B cell CD markers
CD19
T cell CD markers helper
CD4
T cell cytotoxic CD markers
CD8
role of B lymphocytes
made in bone marrow
circulate in blood
mount antigen specific immune response with antibodies
- can neutralise and activate complement
plasma cels
prduce and secrete antigen specific antibodies
name of immature T cells
thymocytes
function of thymus
generate and select T cells
where does positive selection occur
cortext
where does neg selection occur
cortext medulla border
where to T cells undergo diffentiation
medulla
cytotoxic T lymphocytes
recognise and eliminate inefcted cells
CD8
use MCH class 1
how do cytotoxic T cells kill infected cells
secrete IFN to limit viral replicatoin
apoptosis of the cell
T helper cells
help other imune cells become fully functional
CD4
MCH calss 2
polymorphonuclear WBCs
granulocutes
neutrophils
eosinophils
basophils
monoculear WBC
lymphocytes
monocytes
what is granulocotye nomenclature based on
romanoswsy staining
what colour o neutrophols stain?
neutral
what colour do eosinophils stain
orange
