Week 2

Question 1

The hypodermis is made of what tissues ?

Answer 1

Adipose (fat) tissues

Question 2

Keratinocytes are continually dividing with the stem cells in what layer of the epidermis ?

Answer 2

Basal

Question 3

If it say you have skin damage in the superficial layer what layer of skin is this?

Answer 3

Epidermis

Question 4

If u say u have partial thickness damage to the skin what layer of skin is this ?

Answer 4

Into the dermis

Question 5

If u say u have full thickness damage to the skin what layer of skin is this ?

Answer 5

Hypodermis/fascia/ deep tissue

Question 6

what is the most common cellular damage thing to happen to cells?

Answer 6

Ischaemia

Question 7

Answer 7

Question 8

how do you remove free radicals from cells

Answer 8

antioxidants

Question 9

why dose reperfusion lead to tissue death?

Answer 9

sudden influx of oxygen, leads to excess free radical formation
Increase intracellular calcium
either may cause cell damage, inflammation related cell death or apoptosis(programmed cell death)

Question 10

what dose free radical cells damage ?

Answer 10

damage lipids/proteins and DNA

Question 11

Coagulation necrosis

Answer 11

A type of cell death that occurs when blood flow to the cells stops or slows.(inschemia)

Question 12

Liquefactive necrosis

Answer 12

partial or complete dissolution of dead tissue and transformation into a liquid, viscous mass.

Question 13

Caseous necrosis

Answer 13

is a type of cell death that causes tissues to become “cheese-like” in appearance that from the lungs

Question 14

Gangrene

Answer 14

death of body tissue due to a lack of blood flow or a serious bacterial infection.

Question 15

Thombosis

Answer 15

is a blood clot within blood vessels that limits the flow of blood.

Question 16

Fibroblast

Answer 16

A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen,[1] produces the structural framework

Question 17

is a procedure for treating a wound in the skin. It involves thoroughly cleaning the wound and removing all hyperkeratotic (thickened skin or callus), infected, and nonviable (necrotic or dead) tissue, foreign debris, and residual material from dressings.

Answer 17

Debridement

Question 18

Granulated tissue

Answer 18

Granulation tissue is vascularized tissue that forms as chronic inflammation evolves. The new capillaries make the tissue appear pink and granular

Question 19

Epithelialisation

Answer 19

Is the formation of epithelium over a denuded surface ( last stage of wound healing)

Question 20

first intention of wound healing

Answer 20

Healing by first intention or Primary intention healing happens when the wound edges are approximated e.g. by sutures, staples or glue.

Question 21

Granulation

Answer 21

the development of new tissue and blood vessels in a wound during the healing process

Question 22

Secondary Wound healing.

Answer 22

Secondary intention healing means a wound will be left open (rather than being stitched together) and left to heal by itself, filling in and closing up naturally

Question 23

keloid

Answer 23

A raised scar after an injury has healed.

Question 24

Slough

Answer 24

Yellow/white material in the wound bed , its usually wet but can be dry

Question 25

Necrosis

Answer 25

Death of cells due to disease, injury or failure of blood supply or mass cell damage

Question 26

what is the most common type of necrosis? and what is it a result from ?

Answer 26

coagulative necrosis and Ischaemia

Question 27

complications in wound healing what are the 4

Answer 27

1. hypergranulation 2. hypertrophic and keloid scars ( inflammation ?) 3. sloughing and necrosis(dead tissue in wound site) 4. fistula formation (inapproiate connection to organs

Question 28

why does many wound complications happen in tissues?

Answer 28

excessive collagen formation and possibly due to excess inflammation