week 6 Flashcards
(36 cards)
what detects flow rate in the kidneys?
macula densa
what other external mechanism control flow rate in the kidney?
angiotensin will …… filtration rate
increase
noradrenaline will …… filtration rate
decrease
prostaglandins will …… filtration rate
increase
nitrous oxide will …… filtration rate
increase
overalll glomerular filtration rate is determined using what?
creatine
what is acute glomerulonephritis ?
how it treated ?
is damage to the glomerulus leading to protein losses this occurs because of excess immune response in the kidney which cause inflammation and injury to the glomerular basement membrane
treatment with steroids and plasmapheresis
nephrotic syndrome is caused by ?
and treatment
significant damage to the glomerular basement which cause excess protein losses
this can cause oedema ,hyperlipidaemia, increase for thrombosis risk and treatmet is with diuretics
acute renal injury is what?
sudden loss of renal fuction
it is diagnosied by low urine output and increase in creatinine and nitrogen (urea)
what is 3 causes of acute renal injury?
inadequate blood supple(pre-renal)
Damage to Nephron(renal or intra-renal)
ureter blockage(post renal)
What dose RIFLE SCALE stand for ?
it is a messurement of the serverity of kidney injury
RISK
INJURY
FAILURE
LOSS
END-STAGE
What dose oliguria lead to ?
what are the 2most common causes of intrarenal failure
tubular necrosis
. ischaemic
. nephrotoxic
what are the 2most common causes of intrarenal failure
tubular necrosis
. ischaemic
. nephrotoxic
The oliguric phase monitoring and treatment for sodium?
fluid management(adequate with adequate ions)
The oliguric phase monitoring and treatment with potassium
insulin/beta agoinsts/sodium polystyrene sulfonate
The oliguric phase monitoring and treatment foR Creatinine, urine output , sodium, potassium p.H, oedema,urea or anorexia
post renal obstruction inhibits renal outflow the cause of this can because of ?
occlusion of ureter/urethra
or
drug inhibiting bladder contractions, sphincter relaxation
incontinence drug that inhibit cholinergic do what ?
induce bladder contractions
incontinence drugs that stiumlate noradrenaline have what effect on the body?
they effect the urinary sphincters
what symptoms are you going to see in renal injury for
1.risk
2. injury
3. failure
1.risk- none
2. injury -azotemia-high levels of urea in the blood
you may have ——–acidosis, hyperkalaemia-high levels of potassium,oedema
3.you will have azotemia,acidosis,hyperkalaemia,oedema
how is chronic kidney disease diagnosed?
glomerular filtration rates(urine protein (albumin)