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Flashcards in Week 2 formulas Deck (20)
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1

=.6*body wt (kg)

Total body water (TBW) equation

2

=.4*body wt (kg)

intracellular fluids (ICF) equation

3

=.2* body wt (kg)

Extracellular fluids (ECF) equation

4

=2/3TBW

ICF equation as function of TBW

5

=1/3TBW

ECF equation as function of TBW

6

=.75ECF

Interstitial fluid (ISF) equation

7

.25ECF

Plasma equation

8

=amount of indicator (mg)/ [ ] of indicator (mg/ml)

Volume (ml) equation

9

=ECF-Plasma

ISF equation as function of ECF

10

=ISF+Plasma

ECF

11

=ECF-ISF

Plasma

12

=amount of indicator (mg)/avg. [ ] in arterial blood (mg/ml)

Flow in time of 1st passage equation

13

=total amount of drug in body (mg)/plasma [ ] of drug (mg/ml)

Volume of distribution (Vd) formula

14

=6.022*10^23 molecules

1 mole

15

=2 x [Na+] (meq/L)+ ([gluc] (mg/dL)/18) + ([BUN] (mg/dL)/2.8)

Plasma osmolality (Posm) (milliosmolar (mOsm))

16

J=DA(C1-C2)/dX

J=flow of solute (flux) (mol/cm^2 s)

D= diffusion coefficient (cm^2/s)

A=cross-sectional area (cm^2)

dX= thickness (cm)

C1, C2= concentrations (mol/cm^3)

Fick's first law of diffusion

17

=C (membrane) / C(aqueous)

C= [ ] (mol/L)

Partition coefficient (ß) formula

18

J=(D x ß x A (C1-C2)) / dX

J=flow of solute (flux) (mol/cm^2 s)

D= diffusion coefficient (cm^2/s)

A=cross-sectional area (cm^2)

dX= thickness (cm)

C1, C2= concentrations (mol/cm^3)

Fick's first law of diffusion with partition coefficient (ß)

19

J=PA (C1-C2)

J=flow of solute (flux) (mol/cm^2 s)

P= permeability coefficient (cm/s)

A=cross-sectional area (cm^2)

C1, C2= concentrations (mol/cm^3)

Fick's law for diffusion of an uncharged solute

20

J = Kf[(Pc-Pi) – σ(πc-πi)]

Kf = Capillary Filtration Coefficient & includes the capillariy conductivity x area
σ = reflection coefficient for plasma proteins (if impermeant = 1; if freely permeable = 0)

Starling equation