Week 4 (15 questions) Flashcards
What is acyclovir used to treat?
Treatment of HSV1, HSV2, VZV, & Herpes Zoster
Herpes Zoster (Shingles)
Must give medication within?
Give IV acyclovir when?
72 hours of symptom onset
Severe episodes of genital herpes
Acyclovir Specific Client Education
DO NOT DOUBLE DOSE
DO NOT DOUBLE DOSE
Inform clients that this medication is not a cure
Acyclovir will not prevent the spread of infections to others
Get yearly pap because they may be more likely to develop cervical cancer
Tenofovir alafenamide
Indication?
Contraindication?
Adverse effects?
Chronic Hep B infection
End stage renal disease (ESRD)
liver impairment
use cautiously in pregnancy, only if benefit outweighs risk
lactic acidosis
hepatomegaly w/ steatosis
increased liver enzymes
renal failure
Tenofovir alafenamide
Nursing Considerations & Specific Client Education
Client should be tested for HIV infection before starting medication
Advise client to notify HCP immediately if symptoms of lactic acidosis (weakness, fatigue, unusual muscle pain)
Advise females of reproductive potential to notify HCP if pregnancy is planned or suspected of if breastfeeding
Advise clients taking oral contraceptives to use a non-hormonal method of birth control during therapy
Sofosbuvir is used to treat what?
Indication?
Contraindication?
Use of what causes fetal harm?
Chronic Hep C infection
Severe renal impairment
ESRD
concurrent use of St. John’s Wort, and ribavirin (can cause fetal harm)
Sofosbuvir
Nursing Considerations & Specific Client Education
A negative pregnancy test must be obtained immediately before beginning therapy and monthly thereafter*
Instruct client to notify HCP of all medications especially ST. JOHNS WORT
For clients with trouble swallowing, sprinkle pellets on one or more spoonful’s of non-acidic soft foods (pudding or mashed potatoes) at or below room temperature
Take pellets w/in 30 minutes and swallow entire contents;
DO NOT CHEW PELLETS
Highly active antiretroviral therapy (HAART)
Includes several medications
Combo of 2 nucleoside analogues and a protease inhibitor
Nucleoside analogues:
zidovudine
abacavir
emtricitabine
tenofovir
-Protease inhibitor= raltegravir
Zidovudine (HAART)
(treat HIV)
can pregnant women take it?
*Safely used in pregnancy and in newborns
*Causes bone marrow suppression (look at CBC labs)
*Oral or injectable (IV) forms
Zidovudine (HAART)
what does it treat?
Contraindication?
Notrecommended in who?
Adverse effects?
ANEMIA
HIV infection (in combination w/ other retrovirals); reduction of maternal/fetal transmission of HIV
Hypersensitivity
NOT RECOMMENDED IN BREASTFEEDING MOTHERS WITH HIV
Use cautiously in clients with: severe hepatic or renal disease and those with bone marrow suppression
ANEMIA
lactic acidosis
hepatomegaly w/ steatosis
Zidovudine (HAART)
Nursing Considerations & Specific Client Education
Monitor viral load and CD4 counts prior to and periodically during therapy
Monitor CBC q 2 weeks during the first 8 weeks of therapy w/ clients with advanced HIV disease
Instruct client to notify HCP of all Rx, OTC, vitamins, supplements or herbal products
abacavir (HAART)
What’s the purpose?
Decreases viral load and increased CD4 count
INDICATION: HIV infection
Decreases viral load and increase CD4 count
NOT recommended in
breastfeeding mothers with HIV
Use cautiously in clients w/ coronary heart disease
ADVERSE EFFECTS:
CV: myocardial infarction
Fluid & Electrolyte: lactic acidosis
GI: hepatomegaly w/ steatosis
abacavir (HAART)
Nursing Considerations & Specific Client Education
- Monitor viral load and CD4 cell count regularly during therapy
- Must always be used in combination w/ other antiretroviral
drugs (HAART) - Instruct client to notify HCP of all Rx, OTC, vitamins,
supplements or herbal products
emtricitabine (HIV medication) (HAART)
oral only
INDICATION: HIV infection (w/ other antiretrovirals)
CONTRAINDICATION: Hypersensitivity; NOT
recommended in breastfeeding mothers with HIV
Use cautiously in Hep B co-infection (can cause severe exacerbation of HBV)
ADVERSE EFFECTS:
Fluid & Electrolyte: lactic acidosis
GI: hepatomegaly w/ steatosis,
emtricitabine (HAART)
Nursing Considerations & Specific drug education
Monitor viral load and CD4 cell count regularly during therapy
Monitor client for HBV
Women should avoid breastfeeding during therapy
