week 5 reader Flashcards
(42 cards)
interstitial fluid
- a solution that bathes and surrounds the cells + is found in the interstitial spaces
- main component of the extracellular fluid, which also includes plasma and transcellular fluid
- e.g. interstitial fluid is where you have swelling when a bug bites; also where edema occurs
interstitial space
space b/w cell + capillary where interstitial fluid is located
lymphocytopenia
- lower than normal level of lymphocytes in blood, which makes you more prone to fungal + viral infections (whereas low overall WBC count means you would be more prone to bacterial infections)
- associated with increased rates of infection after surgery or trauma
- in HIV patients, low T cell lymphocytes occurs when the HIV virus infects and destroys T cells (specifically, the CD4+ subgroup of T lymphocytes), which are a key part of the immune system
lymphocytosis
- higher than normal level of lymphocytes in blood
- a high lymphocyte coount is usually a sign of a viral infection and indicates that you are in the process of fighting a virus (in some rare case, leukemias are found through an abnormally raised lymphocyte count in an otherwise normal person)
- a high lymphocyte count with a low neutrophil count might be caused by lymphoma
lymphocytopenia vs. lymphocytosis
the two words are antonyms:
- lymphocytopenia is a general decrease in # of lymphocytes
- lymphocytosis is a general increase in # of lymphocytes
neutropenia
- a hematological disorder characterized by an abnormally low # of neutrophil graculocytes (a type of WBC)
- patients with neutropenia are more susceptible to bacterial infections (b/c neutrophils usu. make up 50-70% of circulating WBC’s and serve as the primary defense against infections by destroying bacteria in the blood)
dendritic cell
- dendritic cells can capture antigens + associated peptides using special receptors; the cells then process + display the peptides so that the immune cells organize a response against anything that has that peptide, including cancer cells
- main function is to process antigen material + present it on the surface to other cells of the immune system.
- dentritic cells communicate w/ the whole immune system, acting as messengers between the innate + adaptive immunity
- you can stimulate them using massage + touch therapy
- so-called because the long arm resembles the dendrite of neurons
leukopenia
- a decrease in # of circulating WBC’s (leukocytes) in blood, which places you at increased risk of infection
- aka leukocytopenia, or leucopenia
leukocytosis
- an increase in # of circulating WBCs (leukocytes) in blood
- usu. a discrimating sign that indicates bacterial infection
leukopenia vs. leukocytosis
the two words are antonyms:
- leukopenia is a general decrease in # of leukocytes
- leukocytosis is a general increase in # of leukocytes
lymphadenopathy
- refers to “swollen/enlarged lymph nodes” (although the term means “disease of the lymph nodes”)
- could be due to infection, auto-immune disease, or malignancy
- e.g. “cat scratch disease” where location of swollen lymph nodes indicates area of infection due to bacteria from cat scratch
lymphoma
a tumor of the lymphatic system
burkitt’s lymphoma
- a lymphatic cancer that has special affinity for metastizing quickly + growing in bones
- assoc. w/ epstein-barr virus
- first discovered in equatorial africa
lymphangitis
- an inflammation or infection of the lymphatic channels that occurs as a result of infection at a site distal to the channel
- most common cause is Streptococcus pyogenes (Group A strep)
- signs and symptoms include a deep reddening of the skin, warmth, lymphadenitis, and a raised border around the affected area; the person may also have chills and a high fever along with moderate pain and swelling
large lymphangioma
- a tumor of the lymph system that develops enlarged lymph nodes
- 90% occur in children less than 2 years of age and involve the head and neck
- lymphangiomas are commonly diagnosed before birth using fetal ultrasonography; acquired lymphangiomas may result from trauma, inflammation, or lymphatic obstruction
- since most are benign lesions that result only in a soft, slow-growing, “doughy” mass, they are usually treated for cosmetic reasons only
cardiovascular system
- an organ system that moves substances to/from cells; to/from heart
- general circulation + pulmonary circulation
- in pulmonary circulation, L side of heart collects blood from lung while R side collects blood from veinous system
artery vs. vein
- MUSCULAR TISSUE - arteries have tremendous amount of myo tissue b/c need to conract + dilate; veins don’t need as much myo b/c only function is to collect blood + bring it back to heart
- VALVES - veins have valves that allow blood to only flow one way (like 2 shirt pockets kissing); movement of valves helps circulate blood in veins
diastole
when heart myo relaxes + allows blood to collect in ventricle + atrium
systole
when heart myo contracts, sending blood from the L ventricle to the aorta + body, and from the R ventricle to the lungs
diastole vs. systole
- atrial diastole occurs during ventricle systole
- atrial systole occurs during ventricle diastole
diastole = relaxation systole = contraction
fibrillation
- rapid, irrecular + unsynchronized contraction of myo fibers (b/c myo is made of many diff. fibers)
- e.g. can happen with twitching of the eye when tired
” fibrille” = fibers
fibrillation in heart
- heart myo is not voluntary, and all myo fibers need to work together as one cell for proper function
- ventricular fibrillation is when myo fibers of ventricles are not synchronized – this is a common cause of cardiac arrest and is usually fatal if not reversed by defibrillation; also happens at the moment of death
- atrial fibrillation is a common chronic condition + can be treated
myositis
inflammation or infection of muscle, likely caused by autoimmune conditions
myasteria gravis (MG)
- a neuromuscular disease leading to fluctuating weakness + fatiguability
- causes gradual + progressive weakening of myo (one of first signs is droopy eyelid)
- a genetic condition; associated w/ various autoimmune diseases including thyroid diseases (Hashimoto’s thyroiditis + Graves’ disease), diabetes mellitus type 1, rheumatoid arthritis, lupus
"myastheneia" = muscle disease "gravis" = serious