011915 nutrition biochem Flashcards Preview

Gastrointes 3 > 011915 nutrition biochem > Flashcards

Flashcards in 011915 nutrition biochem Deck (41):
1

how are proteins absorbed in duodenum and jejunum

amino acid transporters (amino acid class specific, dipeptide, tripeptide)

2

fxn of thiamine

cofactor for pyruvate dehydrogenase (pyruvate to acetyl coA)

maintains neural membranes and normal nerve conduction

etc

3

polyneuropathy - dry beriberi

thiamine/vit B1 deficiency

4

Wenicke Korsakoff syndrome (brain pathology)

thiamine/vit B1 deficiency

5

dilated cardiomyopathy

thiamine/vit B1 deficiency

6

fxn of pantothenic acid/vit B5

a part of coenzyme A
part of acl carrier protein for fatty acid synthesis

7

deficiency of pantothenic acid/vit B5 results in

dermatitis, enteritis, alopecia (epithelial cells)
adrenal insufficiency

8

riboflavin/vit B2's fxn

electron carrier (FMN and FAD)

9

cheilosis (scaling and fissures at corners of mouth)

riboflavin/vit B2 defic.

10

riboflavin/vit B2 deficiency results in

cheilosis
dermatitis
corneal neovascularization

11

niacin/vit B3's active forms

NAD, NADH, NADP, NADPH

12

pellagra-3D's

dermatitis, diarrhea, dementia
niacin/vit B3 def

13

glossitis

niacin/vit B3 def

14

fxn of biotin/vit B7

carboxylase cofactor-binds CO2

15

deficiency of biotin/vit B7 results in

dermatitis
alopecia
enteritis

16

pyridoxine/vit B6's active form

pyridoxal phosphate

17

fxn of pyridoxine/vit B6

coenzyme involved in:
--amino acid degradation/conversion
--glycogen degradation
--porphyrin synthesis

18

sideroblastic anemia

pyridoxine/vit B6 defic

19

pyridoxine/vit B6 deficiency results in

convulsions
dermatitis
peripheral nueropathy
sideroblastic anemia

20

fxn of folate/vit B9

carrier of one carbone units for purine synthesis, dTMP synthesis from dUMP, conversion of homocysteine to methionine for SAM synthesis

21

fetal neural tube defects

folate/vit B9 defic
cobalamin/vit B12 defic

22

where is microbiota produced biotin absorbed?

large intestine

23

fxn of ascorbate/vit C

antioxidant (ROS, oxidized vit E)
post translational modification of proteins/collagen
etc

24

scurvy

ascorbate/vit C defic

25

vit E/tocopherol fxn

antioxidant
recycled by vit C

26

hemolytic anemia

vit E/tocopherol defic

27

fxn of vit K/phylloquinone

cofactor for vit K dependent gamma carboxylase

28

vit A forms

beta carotene (antioxidant, vit A precursor)
retinol (vit A)
11-cis retinal (retinaldehyde)-vision
retinoic acid-gene regulation

29

vit A deficiency's effects

night blindness
susceptibility to infec
etc

30

animal form of vitamin D

vit D3

31

active form of vit D

1,25 dihydroxyvitamin D

32

rickets

vit D defic

33

vit D is absorbed where

ileum

34

microbiota produced vit K is absorbed where

large intestine

35

post translational modification-this fxn exists for what vitamins?

K, C

36

gene expression is impacted by what vit

A, D

37

substrate carrier vitamines

thiamine, pantothenic acid

38

absorption of minerals occurs where

stomach and entire intestine

39

zinc's fxn

wound healing, spermatogenesis

40

copper's fxns

antioxidant
electron transport
collagen crosslinking
development

41

selenium's fxns

antioxidant
thyroid hormone fxn