012215 IBD Flashcards Preview

Gastrointes 3 > 012215 IBD > Flashcards

Flashcards in 012215 IBD Deck (13):
1

ulcerative colitis

continuous inflam
colon only
superficial inflam
risk of cancer
extraintestinal manifestations
goes from rectum to more proximal

2

clinical presentation of UC

diarrhea, typically bloody w mucus
abdominal pain
loss of appetite, weight loss
fever
fatigue
urgency for bowel mvmt
children-developmental failure

3

endoscopic findings of UC

erythema
friability (when touched, bleeds)
pseudopolyps (benign)
erosions
ulcers (in severe cases)
cecal patch
backwash ileitis (only w pancolitis)

etc

4

Crohn's dis

pathcy inflam
can involve anywhere from mouth to anus
full thickness inflam (all layers of bowel)
cobblestone look
fistulae-peritoneum, bladder
strictures and surgery (due to inflam)
extraintestinal manifestations

5

most common site for Crohn's dis

terminal ileum, cecum

6

clinical presentation of Crohn's dis

abd pain
diarrhea
weight loss
anorexia
vomiting
rectal bleeding
stunted growth in children
fevers

7

3 major endoscopic findings SPECIFIC for Crohn's dis

aphthous ulcers (canker sores)
cobblestoning
discontinuous lesions

8

you see ulcers more often with Crohn's dis or UC?

Crohn's

9

UC always affects the

rectum

10

fistulas and strictures are seen in Crohn's and not UC b/c

Crohn's has full thickness inflam

11

granulomas on biopsy favors Crohn's or UC?

Crohn's

12

extraintestinal manifestations of IBD

acute arthropathy
erythema nodosum
choledocholithiasis
ocular complications
sacroilliits
ankylosing spondylitis
pyoderma gangrenosum
PSC (more UC than Crohn's)

13

pathogenesis of IBD

genetic-NOD2 mutations
mucosal immune responses (Th17 cells)
epithelial defects (tight jxns)
microbiota (rxns against microbiota)