07 - Virology

Question 1

All enveloped viruses acquire their envelope from the plasma membrane except for:

Answer 1

Herpes virus - acquired from the nuclear membrane

Question 2

All viruses are haploid except for:

Answer 2

retrovirus - diploid

Question 3

Enumerate: RNA viruses with segmented genome (4)

Answer 3

Bunyaviruses
Orthomyxovirus (Influenza)
Arenaviruses
Reoviruses

BOAR

Question 4

Enumerate: Negative-stranded RNA viruses: (6)

Answer 4

Arenaviruses
Bunyaviruses
Paramyxoviruses
Orthomyxoviruses
Filoviruses
Rhabdoviruses

Always Bring Polymerase Or Fail Replication

Question 5

Gold standard in diagnosis of viral infection:

Answer 5

Presence of viral DNA or RNA

Question 6

First vaccine known to prevent a human cancer:

Answer 6

HBV

Question 7

Most common sites of viral infection and disease:

Answer 7

oropharynx and respiratory tract

Question 8

All DNA viruses have double-stranded DNA except:

Answer 8

Parvovirus

Question 9

All DNA viruses have linear DNA except:

Answer 9

Hepadna, Papilloma, and Polyoma

Question 10

All DNA viruses are icosahedral except:

Answer 10

Poxvirus

Question 11

All DNA viruses replicate inside the nucleus except:

Answer 11

Poxvirus (cannot enter the nucleus because of its size)

Question 12

• The only virus with a fiber:

- What is this fiber called?

Answer 12

• Adenovirus

- Penton fiber

Question 13

• Most common viral STD:

- What strains cause this?

Answer 13

• Condyloma accuminata

- HPV 6 and 11

Question 14

The only hepatitis virus whose genome is DNA:

Answer 14

Hepatitis B virus (Hepadna)

Question 15

Enumerate: diseases with blueberry muffin lesions: (3)

Answer 15

• Congenital Rubella
• Congenital CMV
• Disseminated Neuroblastoma

Question 16

• Identify: syndrome of swelling of the liver and brain, leading to encephalitis
• what viral infection can cause this syndrome?

Answer 16

• Reye syndrome

- VZV

Question 17

Most common infectious cause of congenital abnormalities:

Answer 17

congenital CMV infection

Question 18

• Most common cause of blindness in AIDS patients:

- at what CD4 counts does this condition occur?

Answer 18

• CMV retinitis

- CD4 < 40

Question 19

• The only disease that has been eradicated from the face of the earth:
• What is the name of the virus?

Answer 19

• smallpox

- Variola virus

Question 20

Identify: the largest viruses

Answer 20

Variola virus

Question 21

The only DNA virus that produces DNA by reverse transcription with mRNA as the template:

Answer 21

Hepatitis B virus (Hepadnaviridae)

Question 22

All RNA viruses have single-stranded DNA except:

Answer 22

Reovirus and Rotavirus

Question 23

All RNA viruses replicate in the cytoplasm except:

Answer 23

Influenza and Retrovirus

Question 24

Most common cause of myocarditis and pericarditis:

Answer 24

Coxsackie virus

Question 25

Most common clinical form of Polio virus infection:

Answer 25

abortive poliomyelitis

Question 26

Most common cause of aseptic meningtis:

Answer 26

Coxsackie virus

Question 27

Enumerate: (5) viruses of the Picornaviridae family:

Answer 27

- Poliovirus - ECHO (Enteric Cytopathic Human Orphan) virus - Rhinovirus - Coxsackie virus - Hepatitis A virus PERCH on a PIC!

Question 28

Most common cause of nonbacterial diarrhea in adults:

Answer 28

Norwalk virus

Question 29

Most common cause of childhood diarrhea:

Answer 29

Rotavirus

Question 30

Each year, _______ is the most common cause of respiratory tract infections.

Answer 30

Influenza (A)

Question 31

Enumerate: member viruses of the Paramyxoviridae family:

Answer 31

- Parainfluenza virus - RSV (Respiratory Syncytial Virus) - Measles virus - Mumps PaRaMMyxovirus

Question 32

Most important cause of pneumonia and bronchiolitis in infants:

Answer 32

RSV (Respiratory Syncitial Virus)

Question 33

The only vaccine that is routinely used post-exposure:

Answer 33

Rabies virus

Question 34

Most prevalent blood-borne pathogen:

Answer 34

Hepatitis C virus

Question 35

Enumerate: (5) signs of Congenital Rubella Syndrome:

Answer 35

- cataracts - sensorineural deafness - mental retardation - patent ductus arteriosus (PDA) - blueberry muffin baby Bulag, Bingi, Bobo, Butas ang puso, Blueberry Muffin

Question 36

Most complex of the known retroviruses:

Answer 36

HIV

Question 37

Enumerate: (give organism and diagnosis) | AIDS-defining illnesses at CD4 < 500:

Answer 37

- Mycobacterium tuberculosis - disseminated TB - Herpes Simplex Virus - HSV esophagitis - Candida albicans - esophageal candidiasis - Human Herpes Virus 8 - Kaposi sarcoma MHCH!

Question 38

Enumerate: (give organism and diagnosis) | AIDS-defining illnesses at CD4 < 200:

Answer 38

- Pnemocystis jirovecii - PCP pneumonia - Toxoplasma gondii - cerebral toxoplasmosis - Coccidiodes immitis - coccidioidomycosis - Cryptococcus neoformans - meningitis - Crytosporidium parvum - chronic diarrhea PTCCryCry

Question 39

Enumerate: (give organism and diagnosis) | AIDS-defining illnesses at CD4 < 50:

Answer 39

- Mycobacterium avium-intracellulare complex (MAC) - invasive pulmonary disease - Histoplasma - histoplasmosis - Cytomegalovirus - CMV retinitis

Question 40

- These viral strains (2) can cause croup - another name for croup - radiographic sign for croup

Answer 40

- parainfluenza virus 1 and 2 - laryngotracheobronchitis - steeple sign