10/5/12 b Flashcards Preview

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Flashcards in 10/5/12 b Deck (27):
0

Metolazide and idapamide belong to what class of diuretic?

thiazide

2

Pt's w/ _______ should not be given thiazides (or most diuretics).

sulfonamide allergy

3

Thiazides and other non-K+-sparing diuretics risk what acid-base disturbance.

alkalosis

4

The lacunar variant of Reed-Sternberg cells and collagen fibrils are seen in the histopathology of what disease?

nodular, sclerosing Hodgkin's lymphoma

5

In what syndrome do you see esophageal webs?

Plummer-Vinson syndrome

6

What is the main Sx of esophageal webs?

selective dysphagia

7

What are the 3 components of Plummer-Vinson syndrome?

atrophic glossitis, esophageal webs, Fe_def anemia

8

What part of the esophagus do esophageal webs usually occur in?

upper 1/3

9

Pts w/ Plummer-Vinson syndrome are at increased risk of developing what serious disease?

squamous cell carcinoma of the esophagus

10

How many molecules of ATP are normally made from 1 molecule of glucose in normal ANAEROBIC respiration?

2

11

How is CNS toxoplasmosis treated?

pyrimethamine and sulfadiazine

12

What is the classic triad of Wiskott-Aldrich Syndrome?

purpura, eczema, and infections w/ bacteria w/ polysaccharide capsules

13

What are the immunoglobulin levels of Wiskpott-Aldrich syndrome?

low IgM, normal IgG, high IgA/IgE

14

What immunodeficiency shows up later in life in Wiskott-Aldrich Syndrome?

T-cell deficiency

15

What immune deficit characterizes cmmon variable immunodeficiency?

humoral deficiency

16

When does common variable immunodeficiency usu. appear?

late teens/early twenties

17

What is the inheritance pattern of Wiskott-Aldrich?

XR

18

What cardiovascular anomaly, other than coarctation of the aorta, is commonly found in women w/ Turner syndrome?

bicuspid aortic valve

19

Autonomic control of vascular tone is entirely controlled by the _______ nervous system.

sympathetic

20

Which CN is stimulated by stretch of the carotid bodies?

CN IX (glossopharyngeal)

21

Which CN is stimulated by the stretch of the aortic baroreceptors?

CN X (vagus)

22

Within what period of time may thrombolytics be administered to the victim of an ischemic stroke?

3 hrs

23

Why is the effect of alteplase limited to the site of thrombotic occlusion?

plasminogen is activated better in the presence of fibrin

24

What is selegeline?

a centrally-acting MAO-I used in Parkinson's

25

What is the mechanism of action of acyclovir?

gaunosine analog - terminates DNA replication

26

What bone disease is associated w/ celiac sprue?

osteoporosis

27

Ova in the ovaries are arrested in which stage of meosis?

Diplotene stage of Prophase I