10/7/12 Flashcards Preview

Kaplan Qbank > 10/7/12 > Flashcards

Flashcards in 10/7/12 Deck (22):
0

What are the 3 mainstay treatments for acute closed-angle glaucoma?

acetazolamide, Pilocarpine, and mannitol

2

What is pilocarpine? uses?

a muscarinic agonist (M3) used in glaucoma and xerostomia

3

How does clonidine lower blood pressure?

by activating central alpha-2 receptors

4

Medullary sponge kidney is charaqcterized by what histopathology? What clinical problem?

cystic dilation of the collecting tubules; recurrent kidney stones

5

What diuretic would you give to pts w/ medullary sponge kidney and why?

thiazide; reduce Ca++ stone formation

6

How does ADPKD cause increased BP?

reduced glomerular perfusion --> renin

7

What disease causes bone erosion and fractures, plt-penia or pancytopenia, and MΦs w/ "crumpled paper" inclusions?

Gaucher's disease (glucocerebrosidase deficiency)

8

Which 2nd messenger directly causes the release of intracellular calcium when a Gq receptor is stimulated, as in the activation of an α-1 receptor on a smooth muscle cell?

IP3

9

What 2nd messenger directly causes the activation of Protein kinase C after the activation of a Gq -coupled receptor?

DAG

10

Which serovars of Chlamydia trachomatis cause PID and neonatal conjunctivitis?

D-K

11

Which serovars of Chlamydia trachomatis cause trachoma?

A-C

12

Which serovars of Chlamydia trachomatis cause lymphogranuloma venereum?

L1-L3

13

What ligament contains the hepatic portal veins, hepatic artery proper, the common bile duct, and the cystic artery?

hepatoduodenal ligament

14

The ligamentum teres is the adult remnant of what embryonic structure?

umbilical vein

15

The right and left gastric arteries lie w/in what ligament that forms a portion of the lesser omentum?

the gastrohepatic ligament

16

W/in what ligament do the gastroepiploic aa. lie?

gastrocolic

17

What vessels reside w/in the splenorenal ligament?

splenic a. and v.

18

What oncogene is mutated in MEN-I and -II?

ret

19

Which chromosome carries the Wilm's tumor (WT-1) gene?

11

20

Which chromosome carries the RB gene?

13

21

Which chromosome carries the NF-1 gene?

17

22

Which chromosome carries the NF-2 gene?

22