10/7/12 b Flashcards Preview

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Flashcards in 10/7/12 b Deck (23):
0

What oncogene is associated w/ small cell lung cancer?

L-myc (not N-myc!)

1

Single, roughly spherical structures that stain w/ silver stain found in bronchoalveolar lavage w/ biopsy describes _______.

Pneumocystis jiroveci

2

Which vaginal infection causes a grey discharge and a fishy smell?

Gardnerella is grey.

3

Which ameoba will infect the brain's of AIDS pts?

Acanthamoeba

4

What are the Sx of Kallman syndrome?

amennorrhea, lack of secondary sexual characteristics ,and anosmia

5

What is the defect in kallman's syndrome?

inability of the ant. pituitary to secrete FSH and LH

6

Which antifungals are CYP-450 inhibitors? Which HIV drugs?

Azoles; protease inhibitors (e.g. indinavir, saquinavir)

7

Hi BP and proteinuria before 20 wks gestation is suggestive of _______.

hydatidiform mole

8

What jaundice-causing disease is especially asscoiated w/ ulcerative colitis?

primary sclerosing cholangitis

9

What characterizes prmary scleosing cholangitis on ERCP?

"beading" appearance of bile ducts - alternating strictures and dilation

10

What are the special lab characteristics that differentiate GBS from other forms of Strep?

CAMP (+) (incomplete hemolysin) and bacitracin resistant

11

Which fibers detect changes in muscle length and initiate tendon reflexes?

spindle afferents

12

What neurons form the efferent part of the tendon reflex arc?

alpha motor neurons

13

Which muscle fibers attach to spindle afferents and other proprioceptors?

intrafusal fibers

14

What muscle fibers form the bulk of the muscle and do most of the contracting?

extrafusal fibers

15

How does parvovirus B19 usually manifest in the adult?

transient arthralgia

16

What ToRCHeS infection causes cutaneous hemorrhages, periventricular calcification, and deafness?

CMV

17

Which ToRCHeS infection causes PDA, pulmonary stenosis, developmental problems, and blindness?

rubella

18

What 3 (kinds of) conditions are target cells most commonly seen in?

thalassemias, Hb C disease, and liver disease

19

What drugs often used to treat sequelae of metabolic syndrome will maks the signs of hypoglycemia?

beta-blockers

20

What is methyldopa?

a centrally-acting alpha-agonist used for refractory htn

21

Which apoprotein activates LPL, and is responsible for a rare form of primary hyperlipidemia, w/ esp. hi TGs?

C-II

22

Which complement component is the most important for remnoval of immune complexes?

C3b