Pregnancy Flashcards

1
Q

how long is the menstrual cycle normally?

A

28 days long

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2
Q

when does the menstrual cycle begin?

A

menstruation

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3
Q

what are the two phases of the menstrual cycle?

A

follicular phase

luteal phase

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4
Q

what is the first half of the menstrual cycle called?

A

follicular phase

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5
Q

what happens in the follicular phase?

A

ovum develops in the follicle

oestrogen produced by the follicle

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6
Q

when does LH peak?

A

at around 14 days

just before ovulation

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7
Q

what happens to the follicle after ovulation?

A

becomes the corpus luteum

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8
Q

what is the second half of the menstrual cycle called?

A

the luteal phase

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9
Q

what does the luteum do?

A

grows and produces progesterone

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10
Q

what happens if fertilisation does not occur?

A

the luteum dies off

menstrual cycle starts again

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11
Q

what hormone does the ovum produce?

A

oestradiol

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12
Q

what hormone does the corpus luteum produce?

A

progesterone

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13
Q

what hormone does the implanted zygote produce?

A

HCG

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14
Q

what hormone is picked up by a pregnancy test?

A

HCG

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15
Q

what three hormones are produced by the placenta?

A

human placental lactogen (HPL)
placental progesterone
placental oestrogens

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16
Q

what causes insulin resistance in a pregnant mother?

A

placental progesterone

HPL

17
Q

what are the three types of diabetes found in pregnancy?

A

type 1
type 2
gestational

18
Q

what is gestational diabetes?

A

diabetes that comes on during pregnancy and will go away after

19
Q

when does foetal organogenesis start?

A

5 weeks gestation

20
Q

what are some complications associated with T1 and T2Dm in pregnancy?

A

malformation
prematurity
IUGR

21
Q

what are some complications associated with all types of diabetes in pregnancy?

A

macrosomia
polyhydramnios
intrauterine death

22
Q

what is macrosomia?

A

baby >90th centile for size

23
Q

what is polyhydraminos?

A

increased amniotic fluid around the baby

24
Q

name three possible complications that can affect babies of diabetic mothers after birth

A

respiratory distress
hypoglycaemia
hypocalcaemia

25
Q

what should be prescribed for all diabetic women who become pregnant?

A

folic acid 5mg

at least 3 months prior to conception if possible

26
Q

when are eye checks done in pregnancy for diabetic patients?

A

every 10 weeks

20 week check can be skipped if week 10 clear

27
Q

what medications can be given for blood pressure in pregnancy?

A

labetalol
nifedipine
methyldopa

28
Q

what blood pressure drugs should be avoided in pregnancy?

A

ACEi

statins

29
Q

what medication should be started in all high risk pregnancies and why?

A

aspirin 150mg at 12 weeks

reduces risk of pregnancy induced hypertension

30
Q

what should be done in the post-natal period for someone with gestational diabetes?

A

6 week post natal fasting glucose or OGTT to ensure resolution of diabetes

31
Q

what impact can thyroid disease have on fertility?

A

result in anovulatory cycles

32
Q

what are anovulatory cycles?

A

menstrual cycles without ovulation

33
Q

what is maternal thyroxine important for during foetal development?

A

development of the CNS

34
Q

what should be done for patients on levothyroxine if they become pregnant?

A

dose should be increased ASAP

35
Q

what effect does HCG have on thyroid hormones?

A

suppresses TSH

causes high T4

36
Q

what does high HCG cause?

A

hyperemesis

37
Q

what anti-thyroid drugs can be used in pregnancy?

A

propylthiouracil in semester 1

carbimazole in the others