Autoimmune Disease 2 Flashcards
1
Q
Examples of molecular mimicry?
A
Autoimmune haemolysis after mycoplasma pneumoniae, i antigen homologous to red blood cell antigens
Rheumatic fever, streptococcal infection
2
Q
T1D prevalence?
A
0.8%, rising by 5% ever year
3
Q
By the time you develop diabetes what percent of pancreas is destroyed?
A
90%
4
Q
HLA alleles for type 1 diabetes?
A
DR3 and DR4
5
Q
What could be a possible cause of T1D?
A
Coxsackie virus, causes pancreatitis and precipitate autoimmune diabetes
Protein 2C has homologous with islet cell antigen glutamic acid decarboxylase
6
Q
LUPUS signs?
A
Butterfly rash Photosensitivity Hives Serositis, pulmonary fibrosis Joint pain Autoimmune cytopenia
