Antigen P&P- Part 1

Question 1

What type of cells recognize antigens that are processed and presented by antigen-presenting cells?

Answer 1

T cells

Question 2

Both foreign and self-antigens can be ___________ and _________

Answer 2

Processed and presented

Question 3

ALL _________ cells, which express MHC molecules, can serve as antigen-presenting cells

Answer 3

Nucleated

Question 4

What type of cells do not have a nucleus and cannot serve as antigen-presenting cells?

Answer 4

Mature RBCs

Question 5

What are T cells that have never encountered an antigen?

Answer 5

Naive T cell

Question 6

What are the 3 professional antigen-presenting cells?

Answer 6

Dendritic cell
B cell
Macrophage

Question 7

What is the one major type of antigen-presenting cell that can activate naive T cells?

Answer 7

Dendritic cells (DC’s)

Question 8

DC’s are at least ____ times more effective APC’s than macrophages or B cells

Answer 8

100

Question 9

Why can dendritic cells, but not B cells or macrophages, activate naive T cells?

Answer 9

Mature dendritic cells can assemble complete T cell activation complexes such as peptide/HHC complexes and constimulatory molecules