Cytokines&Receptors- Functions

Question 1

What is the effect: bind to receptors on the cell that produce them?

Answer 1

Autocrine/Intracrine Effect

Question 2

What is the effect: bind to receptors on nearby cells?

Answer 2

Paracrine cells

Question 3

What is the effect: Bind to receptors on the cells in distant locations?

Answer 3

Endocrine effect

Question 4

What is a given cytokine has different biological effects on target cells?

Answer 4

Pleiotropic action

Question 5

What target cell of a cytokine has the effect of activation, proliferation, differentiation?

Answer 5

B cell

Question 6

What 2 target cells of a cytokine have the effect of proliferation?

Answer 6

Thymoctye and Mast cells

Question 7

Two or more cytokines exert the same biological effect on the same cells??

Answer 7

Redundancy

Question 8

What is: the effect of two cytokines on a particular cell is greater than the additive effect of individual cytokines?

Answer 8

Synergistic action

Question 9

What type of action is the following an example of?
Activated Th cell -> IL 4+IL-5 -> B cell whose effect = induces class switch to IgE

Answer 9

Synergistic action

Question 10

What is: the action of one side of cytokine inhibits the effects of another cytokine?

Answer 10

Antagonistic action

Question 11

What is: The action of a cytokine leads to the induction of one or more cytokines, which in turn induces the production of other cytokines?

Answer 11

Cascade action