CH.14 Flashcards
how are immune complexes removed from the blood
phagocytosis, spleen
where do immune complexes accumulate if they are not removed
blood vessel walls and tissues where blood is filtered
what type of hypersensitivity rxn is removing immune complexes on filtering tissues
type III
what happens to the tissues once a type III rxn occurs
damages the tissue and causes inflammation
def? exaggerated immune response to a typically harmless ag
hypersensitivity
what type of hypersensitivity has immediate rxns
Type I, II, and III
what type of hypersensitivity has delayed rxn
type IV
what is the immune mediator for type I
IgE
type of hypersensitivity? Ag causes cross linking of IgE bound to mast cells which causes release of vasoactive mediators
Type I
what cause type I hypersensitivity rxn
allergies
what is the immune mediators for Type II hypersensitivity
IgG or IgM
type of hypersensitivity? Ab directed against cell surface ag mediates cell destruction (complement)
type II
what causes type II hypersensitivity rxns
blood transfusions
what is the immune mediator for type III rxn
immune complexes
type or hypersensitivity? Ag-ab complexes deposited in tissues induce complement and inflammation by infiltration of neutrophils
type III
