Chapter 12 Flashcards
What makes vitamins essential?
body doesn’t make them (organic)
How many essential vitamins are there?
13
How many water-soluble vitamins are there?
9
Thiamin (B1)
Riboflavin (B2)
Niacin (B3)
Pantothenic Acid (B5)
Biotin
Pyridoxine (B6)
Folate (B9)
Cobalamin (B12)
Vitamin C
How many fat-soluble vitamins are there?
4- Vitamin A, D, E, K
What are some of the vitamins involved in energy metabolism?
B1,B2,B3, PA, and Biotin
What is megaloblastic anemia?
Cells are big and immature (Macrocytic)
What is pernicious anemia?
cells are big and too few (Macrocytic)
Which nutrient deficiencies can cause megaloblastic anemia?
Folate deficiency
What are some of the functions of vitamins?
-cell growth
-energy metabolism (coenzymes)
-antioxidant defense
-immunity
-blood clotting
-collagen
-neurotransmitter synthesis
How much do humans typically need of vitamins and macronutrients?
Macronutrients= g
Vitamins= mcg or mg range
What are some of the conditions associated with an iodine deficiency?
goiter and cretinism
What is a pharmacologic dose?
very high doses
Which vitamin is supplemented in high doses to lower blood lipid levels?
niacin
-brings up HDL levels
One side effect of supplementing niacin in high doses?
niacin flush
Vitamin E is more potent in which form?
natural form
d prefix
natural form
dl prefix
synthetic
Which is more biologically active, folate or folic acid?
folic acid
What are four vitamins/minerals that are better absorbed when your body produces adequate stomach acid?
calcium, iron, zinc, vitamin C
Fat-soluble vitamins absorbed with?
dietary fat
Water-soluble vitamins are absorbed how?
independent of dietary fat
What are some diseases that could impact the absorption of fat-soluble vitamins?
pancreatic disease, intestinal disease, liver disease
Why are fat-soluble nutrients more likely to cause toxicity side effects?
accumulate in adipose tissue
Wernicke Korsakoff syndrome (WKS)
cause: alcohol abuse
symptoms: confusion, ataxia, weakness, peripheral neuropathy
Which vitamin does alcohol impair the digestion, absorption, storage of?
Thiamin: important in the metabolism of energy, which is why people with WKS experience neurological side effects
Fat-soluble vitamins transport?
chylomicrons-> lymphatic system-> bloodstream-> adipose tissue & liver
Water-soluble vitamins transport?
absorbed directly into bloodstream and distributed throughout the body
What fat-soluble vitamin is produced by the bacteria in the gut?
small amounts of vitamin K and biotin
How are vitamins transported in the body?
chylomicrons
Which two fat-soluble nutrients are most likely to cause toxicity side effects?
Vitamin A & D
Why are water-soluble vitamins less likely to cause toxicity?
excreted in urine
Vitamin toxicity rare?
food consumption