5-killers viruelensfaktorer Flashcards

1
Q

s. pyogenes (GAS)

A
  1. M protein
    - adhesin
    - hindrar fagocytos och komplementaktivering genom att binda Fc-del av AK
    - superantigen
  2. kapsel
  3. fagocytoshämning: bryter ner komplement med enzym
  4. hydrolytiska enzym: streptokinas, streptolysin
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2
Q

beta-hemolys

A

komplett hemolys

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3
Q

s. aureus

A
  1. exotoxin
    - alfa-toxin: skadar cellmembran
    - toxin chock toxin-1 (superantigen)
  2. cell-cell kommunikation
  3. peptidas och penicillins
  4. ytprotein: adhesion
    - protein A: binder Fc-del av IgG
    - fibronektinbindande, kan klä in sig och gömma sig
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4
Q

pneumokock

A

kapsel
- adhesion, skydd fagocytos, binder komplement

enzymer
- autolysin
- pneumolysin

ytprotein: adhesion, gömma sig

sIgA-proteas
- undkommer slemhinne-IF

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5
Q

neisseria meningitidis

A

obs koppling till brist i komplementsystemet
- utred
- vaccinera

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6
Q

virulens meningkock

A

adhesion: pili

poriner som lyserar värdcell

sIgA-proteas

transferrinbindande protein

endotoxin
- LPS

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