Integrated Control Of Bp Flashcards
Blood pressure =
Cardiac output X TPR
Cardiac output=
Stroke volume x HR
Baro receptors located many in:
Aortic arch and carotid sinus
Characteristics of baroreceptors?
Unmyelinated nerve fibres
Stretch sensitive
Respond to the magnitude of pressure change and rate of change
Blood pressure regulation centre is?
Nucleus tractus solitarius NTS
Beginning of the vagus nerve is called?
Nucleus ambiguus
NTS has 2 nerves:
Activates nucleus ambiguus
Activates nerve At CVLM which inhibits nerve at RVLM
Rostral ventrolateral medulla RVLM define
Brain region that is responsible for basal and reflex control of sympathetic activity associated with cardiovascular function
Pressor area of the medulla known as
RVLM
Nerves in RVLM are?
Sympathetic that go to heart/ blood vessels
RVLM receives what signal from CVLM?
Inhibitory GABAergic input
CVLM function
Inhibits RVLM
Stretch receptor: increase in stretch ( increase MAP) physiology:
Increased BR firing:
Increase PNS ( parasympathetic vagal tone) activation → increase in ACh → decreased HR
AND
Decrease SNS (more inhibition) → decrease in NA → decreased HR and TPR
Stretch receptor: decrease in stretch ( increase MAP) physiology:
Decreased BR firing: ‘
Decrease PNS ( parasympathetic vagal tone) activation → decrease in ACh → increased HR
AND
Increase SNS ( less inhibition) →increase in NA →increased HR and TPR
Baroreflex function
Adjusts CO and peripheral vascular tone to stabilise arterial pressure
